Results 31 to 40 of about 62,974 (250)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Fluorescence Properties of LED Phosphoric Acid Rare Earth Phosphor
Chemical Engineering Transactions, 2016 As a new type of light source in twenty-first Century, energy saving and environmental protection, long use time, and high luminous efficiency are the advantages of white LED compared with the traditional incandescent lamp and fluorescent lamp.
Y. Huang
doaj +1 more source
Chinese Medical Journal, 2019 Nickel-induced allergic contact dermatitis (Ni-ACD) is a global health problem. More detailed knowledge on the skin uptake of haptens is required. This study aimed to investigate the penetration process and distribution of nickel in skin tissues with late phase and early phase of Ni-ACD to understand the mechanisms of metal allergy.Forty Hartley guinea
Shan-Qun Jiang +14 more
openaire +3 more sources
A new method for x-ray fluorescence analysis of contaminated material. Final Report [PDF]
, 2002 Niton has successfully completed the objectives of the Phase II program to build a hand-held, x-ray fluorescent analyzer optimized for DOE decontamination and decommissioning activities in the field.
Niland, John, Grodzins, Lee
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Catalyst analysis using synchrotron x-ray microscopy [PDF]
, 1990 Synchrotron x-ray microscopy techniques have been used to characterize several different types of heterogeneous catalysts. Using a collimator to produce microbeams with a size of less than 10 micrometers, maps of the elemental distributions based on ...
Conner, W. C. +6 more
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Structural DynamicsMicrocrystal Electron Diffraction (MicroED) is an emerging CryoEM technique that enables high-resolution structure determination of biological molecules by analyzing electron diffraction patterns from single micro- or nanocrystals on EM grids.
Anna Shiriaeva
doaj +1 more source
Produção e estudo de sulfetos de níquel nanométricos com substituição parcial de paládio [PDF]
, 2015 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Física, Florianópolis, 2015.O sulfeto de níquel, em sua estequiometria [Ni]:[S] ?
Semione, Guilherme Dalla Lana
core
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source