Results 91 to 100 of about 861,603 (331)

Cytogenetics of Premature Ovarian Failure: An Investigation on 269 Affected Women [PDF]

, 2011
The importance of X chromosome in the aetiology of premature ovarian failure (POF) is well-known but in many cases POF still remains idiopathic. Chromosome aneuploidy increase is a physiological phenomenon related to aging, but the role of low-level sex
Angela Bentivegna, Anna Marozzi, Donatella Conconi, Elena Panzeri, Elena Sala, Emanuela Martinoli, Fabiana Saccheri, Francesca Crosti, Leda Dalprà, Marinella Volontè, Nicoletta Villa, Sara Lissoni, Serena Redaelli, Simona Baronchelli   +13 more
core   +3 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Neocentric X-chromosome in a girl with Turner-like syndrome

Molecular Cytogenetics, 2012
Background Neocentromeres are rare human chromosomal aberrations in which a new centromere has formed in a previously non-centromeric location. We report the finding of a structurally abnormal X chromosome with a neocentromere in a 15-year-old girl with ...
Hemmat Morteza, Wang Boris T, Warburton Peter E, Yang Xiaojing, Boyar Fatih Z, El Naggar Mohammed, Anguiano Arturo   +6 more
doaj   +1 more source

Automated clinical system for chromosome analysis [PDF]

, 1978
An automatic chromosome analysis system is provided wherein a suitably prepared slide with chromosome spreads thereon is placed on the stage of an automated microscope.
Castleman, K. R., Friedan, H. J., Johnson, E. T., Rennie, P. A., Wall, R. J.   +4 more
core   +1 more source

Mismatches between the genetic and phenotypic sex in the wild Kou population of Nile tilapia Oreochromis niloticus [PDF]

, 2019
Sex determination and sex chromosomes can be very diverse between teleost species. The group of tilapias shows a polymorphism in sex determination not only between closely related species but also between domestic strains within a species.
Baroiller, Jean-François, D'Cotta, Helena, Sissao, Rokyatou, Toguyeni, Aboubacar   +3 more
core   +1 more source

X X-Chromosom

, 2016
Arbeit am ...
openaire   +2 more sources

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

\u3cem\u3eAnolis\u3c/em\u3e Sex Chromosomes Are Derived from A Single Ancestral Pair [PDF]

, 2014
To explain the frequency and distribution of heteromorphic sex chromosomes in the lizard genus Anolis, we compared the relative roles of sex chromosome conservation versus turnover of sex‐determining mechanisms. We used model‐based comparative methods to
Gamble, Tony, Geneva, Anthony J., Glor, Richard E., Zarkower, David   +3 more
core   +1 more source

Relation between mutation yield and cell lethality over a wide range of X-ray and fission neutron doses in maize [PDF]

, 1973
Dry maize seeds, of a genetic stock heterozygous for the yellow-green locus (Yg^ Λ ^ ) ι were irradiated with fission neutron doses up to 2700 rads and with 250 kVp X-rays to 40 000 rads.
Kellerer, Albrecht M., Rossi, H. H., Smith, H. H.   +2 more
core   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source