Results 131 to 140 of about 6,270,911 (362)
A region‐wise functional connectivity dynamics (FCD) switching index (RFSI) identifies abnormal drivers in ASD across development, linked to salience/ventral attention, default mode, and frontoparietal networks. RFSI changes correlate with transcriptomic and neurotransmitter profiles, and supported by gene‐edited ASD monkeys.
Wei Li+11 more
wiley +1 more source
Identification of candidate novel production variants on the Bos taurus chromosome X
: Chromosome X is often excluded from bovine genetic studies due to complications caused by the sex specific nature of the chromosome. As chromosome X is the second largest cattle chromosome and makes up approximately 6% of the female genome, finding ...
H. Trebes+10 more
doaj
Application of Generalised sequential crossover of languages to generalised splicing [PDF]
This paper outlines an application of iterated version of generalised sequential crossover of two languages (which in some sense, an abstraction of the crossover of chromosomes in living organisms) in studying some classes of the newly proposed generalised splicing ($GS$) over two languages. It is proved that, for $X,Y \in \{FIN, REG, LIN, CF, CS, RE \}
arxiv
THE MEIOTIC BEHAVIOR OF GROSSLY DELETED X CHROMOSOMES IN DROSOPHILA MELANOGASTER [PDF]
Dan L. Lindsley, L Sandler
openalex +1 more source
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang+17 more
wiley +1 more source
Discovery of Phylogenetic Relevant Y-chromosome Variants in 1000 Genomes Project Data [PDF]
Current Y chromosome research is limited in the poor resolution of Y chromosome phylogenetic tree. Entirely sequenced Y chromosomes in numerous human individuals have only recently become available by the advent of next-generation sequencing technology. The 1000 Genomes Project has sequenced Y chromosomes from more than 1000 males.
arxiv
Hepatoblastoma, an aggressive childhood liver tumor, origins from malignant hepatoblast‐like cells. Single‐cell analysis reveals IGF2‐driven pathways promoting malignancy. Targeting these pathways offers promising treatments, with serum IGF2 as a potential diagnostic biomarker.
Miao Ding+12 more
wiley +1 more source
A FURTHER ANALYSIS OF LOCI IN THE SO-CALLED "INERT REGION" OF THE X CHROMOSOME OF DROSOPHILA [PDF]
Hermann J. Müller+3 more
openalex +1 more source
A 3D Genome Atlas of Genetic Variants and Their Pathological Effects in Cancer
The hierarchical organization of the eukaryotic genome is vital for nuclear function, and disruptions from genetic mutations can alter this 3D architecture. Cataloging thousands of interchromosomal translocations, structural variants, and single nucleotide polymorphisms, their impact on 3D genome organization is revealed. The scoring algorithm, 3DFunc,
Li Tang+6 more
wiley +1 more source