Results 201 to 210 of about 6,305,601 (337)

Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes

Advanced Science, EarlyView.
This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo, Josephine A. Robertson, Andrea Aparicio, Kirsten Seale, Qingwen Chen, Anne Richmond, Zhaozhen Du, Mahnoor Sulaiman, Shijie C Zheng, Esteban Ballestar, Charlotte AM Cecil, Bastiaan T Heijmans, Steve Horvath, Varun B. Dwaraka, Jessica Lasky‐Su, Ryan Smith, Riccardo E. Marioni, Andrew E Teschendorff   +17 more
wiley   +1 more source

Genetic analysis of an asymptomatic female with a large Xp deletion revealed insights into the X chromosome inactivation pattern: a case report. [PDF]

Mol Cytogenet
Zhang LJ, Liu WL, Shao SY, Xu Y, Zhou L.
europepmc   +1 more source

THE MEIOTIC BEHAVIOR OF TANDEM ACROCENTRIC COMPOUND X CHROMOSOMES IN DROSOPHILA MELANOGASTER [PDF]

, 1963
L Sandler, D L Lindsley
openalex   +1 more source

Super‐Resolution Compatible DNA Labeling Technique Reveals Chromatin Mobility and Organization Changes During Differentiation

Advanced Science, EarlyView.
A novel chromatin‐labeling probe is developed to investigate chromatin mobility during differentiation. The silicon rhodamine–conjugated dCTP is efficiently delivered into iPSCs and NSCs using a synthetic transporter. Super‐resolution microscopy and single‐particle tracking show decreased chromatin mobility during differentiation.
Maruthi K. Pabba, Miroslav Kuba, Tomáš Kraus, Kerem Celikay, Janis Meyer, Sunil Kumar Pradhan, Andreas Maiser, Hartmann Harz, Heinrich Leonhardt, Karl Rohr, Michal Hocek, M. Cristina Cardoso   +11 more
wiley   +1 more source

Role of X chromosome and dosage-compensation mechanisms in complex trait genetics. [PDF]

Am J Hum Genet
Fu Y, Kenttämies A, Ruotsalainen S, Pirinen M, Tukiainen T.   +4 more
europepmc   +1 more source

The Influence of X-ray Treatment on the Wheat Crosses between Species having Different Number of Chromosomes (A Preliminary Note)

, 1938
M. Tanaka
openalex   +2 more sources

Nanocatalytic Neuroprotection and Neurological Recovery Post‐Traumatic Brain Injury

Advanced Science, EarlyView.
This study demonstrates that combining Ce0.7Zr0.3O2 nanozymes with nimodipine enhances neuroprotection after traumatic brain injury. The therapy reduces oxidative stress, neuronal apoptosis, and improves blood–brain barrier integrity, with nanozymes effective at low doses.
Xinjie Hong, Liang Zhao, Xianzheng Sang, Chao Ma, Meiqi Chang, Xinran Song, Wei Feng, Tao Xu, Li Ding, Yu Chen, Lijun Hou   +10 more
wiley   +1 more source

FemXpress: Systematic Analysis of X Chromosome Inactivation Heterogeneity in Female Single-Cell RNA-Seq Samples. [PDF]

Adv Sci (Weinh)
Wang X, Ma Y, Li F, Cui W, Pan T, Wang S, Ma S, Shan Q, Liu C, Wang Y, Zhang Y, Zhou Y, Li W, Wang P, Zhou Q, Feng G.   +15 more
europepmc   +1 more source

Klinefelter's syndrome with a presumptive deleted X chromosome. [PDF]

, 1966
Jørgen Nielsen
openalex   +1 more source

Molecular Chain Elongation Mechanism for n‐Caproate Biosynthesis by Megasphaera Hexanoica

Advanced Science, EarlyView.
The medium‐chain carboxylate‐producing microbe Megasphaera hexanoica is analyzed through genomics, transcriptomics, and metabolic engineering. The n‐caproate biosynthetic pathway is reconstructed in Escherichia coli, highlighting MhTHL as a key β‐ketothiolase. Structural analysis and mutagenesis reveal that MhTHL has a distinct substrate‐binding pocket,
Byoung Seung Jeon, Eun‐Jung Kim, Hogyun Seo, Hyunjin Kim, Seungjin Shin, Caroline Schlaiß, Largus T. Angenent, Kyung‐Jin Kim, Byoung‐In Sang   +8 more
wiley   +1 more source