Results 211 to 220 of about 861,603 (331)

Genetic Regulation of Alternative Polyadenylation Provides Novel Insights into Molecular Mechanisms Underlying Non‐small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Compared with the non‐risk G allele of rs9606, the risk T allele of rs9606 decreases the binding affinity of NUDT21 for LYRM4, triggering 3'UTR shortening that stabilizes LYRM4 mRNA and elevates its expression. Increased LYRM4 expression promoted malignant phenotypes of non‐small cell lung cancer (NSCLC) cells through modulating ferroptosis, supporting
Meng Jin   +11 more
wiley   +1 more source

X-linked Deficiency in ELF4 in Females with Skewed X Chromosome Inactivation. [PDF]

open access: yesJ Clin Immunol
Zhao R   +13 more
europepmc   +1 more source

Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1

open access: yesAdvanced Science, EarlyView.
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo   +10 more
wiley   +1 more source

Aging activates escape of the silent X chromosome in the female mouse hippocampus. [PDF]

open access: yesSci Adv
Gadek M   +12 more
europepmc   +1 more source

H 3 -THYMIDINE UPTAKE BY A RING X CHROMOSOME IN A HUMAN FEMALE

open access: green, 1964
Janet D. Rowley   +3 more
openalex   +2 more sources

Home - About - Disclaimer - Privacy