Results 251 to 260 of about 6,305,601 (337)

Hepatic CBP/p300 Orchestrate Amino Acid‐Driven Gluconeogenesis through Histone Crotonylation

Advanced Science, EarlyView.
Hepatic CBP/p300 control amino acid‐driven gluconeogenesis by modulating histone crotonylation. This study identifies 2‐aminoadipate (2‐AAA) as a key metabolite that enhances crotonylation and activates amino acid and gluconeogenic gene expression.
Chunxiang Sheng, Tianjiao Li, Hong Lin, Xiaoqin Ma, Feiye Zhou, Mingzhu Li, Yiru Wang, Shushu Wang, Jialin Tan, Junmin Chen, Yulin Yang, Jianmin Liu, Yufang Bi, Jieli Lu, Xiao Wang, Libin Zhou   +15 more
wiley   +1 more source

Microglial response to amyloid-β pathology is modulated by X chromosome dosage

Arancibia-Carcamo IL, Davis E, Gatto N, Meleckyte R, Varsally W, Mitchener V, Thackray M, Fiers M, De Strooper B, Turner J.   +9 more
europepmc   +1 more source

THE MEIOTIC BEHAVIOR OF TANDEM ACROCENTRIC COMPOUND X CHROMOSOMES IN DROSOPHILA MELANOGASTER

, 1968
John R. Merriam
openalex   +2 more sources

siRNAs from an X-linked satellite repeat promote X-chromosome recognition in Drosophila melanogaster

Proceedings of the National Academy of Sciences of the United States of America, 2014
Debashish U. Menon, C. Coarfa, W. Xiao, P. Gunaratne, V. Meller   +4 more
semanticscholar   +1 more source

Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer

Advanced Science, EarlyView.
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou, Cheng‐Wei Ju, Nicholas A. Egan, Yanjun Wei, Yunfei Wang, Minghao Dang, Tianyi Zhou, Leilei Shi, Ningbo Zheng, Si Chen, Ashley M. Guerrero, Xiaofang Liang, Wanfu Wu, Areej Akhtar, Chitra Dhiman, Debanwita Roy Burman, Andro E. Gerges, Mason D. Flores, Han Li, Li‐Sheng Zhang, Marleen Kok, Xiaobo Mao, Linghua Wang, Qin Feng, Yiwen Chen, Sanghoon Lee, Daniel J. McGrail, Nidhi Sahni, Chuan He, Amir A. Jazaeri, Weiyi Peng   +30 more
wiley   +1 more source

The maternal X chromosome affects cognition and brain ageing in female mice. [PDF]

Nature
Abdulai-Saiku S, Gupta S, Wang D, Marino F, Moreno AJ, Huang Y, Srivastava D, Panning B, Dubal DB.   +8 more
europepmc   +1 more source

ggalign: Bridging the Grammar of Graphics and Biological Multilayered Complexity

Advanced Science, EarlyView.
The ggalign package provides a comprehensive framework for composable visualization built on top of ggplot2. Its primary purpose is to enable the construction of complex multi‐plot layouts with consistent observation alignment across plots, particularly for high‐dimensional data contexts such as genomics, transcriptomics, and microbiome studies ...
Yun Peng, Shan Jiang, Yuxuan Song, Peng Luo, Jianfeng Li, Dehua Hu, Jian‐Guo Zhou, Guangchuang Yu, Tao Xu, Shixiang Wang   +9 more
wiley   +1 more source

Cattle T2T X Chromosome: Insights into Natural Neocentromere Evolution

Low W, Pineda P, Macphillamy C, Ren Y, Chen T, Zhong L, Adelson D, Dessaix C, Perez-Silva J, Haggerty L, Martin F, Bottema C, Pitchford W, Rosen B, Smith T.   +14 more
europepmc   +1 more source

Benchmarking Ploidy Estimation Methods for Bulk and Single‐Cell Whole Genome Sequencing

Advanced Science, EarlyView.
It comprehensively benchmarks computational tools for ploidy estimation from bulk and single‐cell whole‐genome sequencing data. The results highlight the strengths and limitations of each method under different conditions and identify PURPLE and SeCNV show top performance in bulk and single‐cell settings, respectively.
Yawei Song, Zilv Mei, Qijie Zheng, Qingqing Yuan, Yu Liang, Jiaqi Gao, Lang Zhou, Shuheng Wu, Wei Wu   +8 more
wiley   +1 more source