Results 281 to 290 of about 6,270,911 (362)

DEPENDENCE OF FREQUENCY OF X-RAY-INDUCED CHROMOSOME ABERRATIONS ON DOSE RATE IN THE CHINESE HAMSTER

, 1963
J.G. Brewen
openalex   +1 more source

Genetic and pharmacological reactivation of the mammalian inactive X chromosome

Proceedings of the National Academy of Sciences of the United States of America, 2014
Sanchita Bhatnagar, Xiaochun Zhu, Jianhong Ou, Ling-ju Lin, Lynn Chamberlain, L. Zhu, N. Wajapeyee, Michael R. Green   +7 more
semanticscholar   +1 more source

Self‐Propelled In Situ Polymerized Nanoparticles Activating the STING Pathway for Enhanced Bladder Cancer Immunotherapy

Advanced Science, EarlyView.
A self‐propelled nanomedicine delivery system forms DMCU nanoparticles in the bladder via in situ polymerization of dopamine hydrochloride, Mn2+, cGAMP, and urease. The urease‐driven propulsion enhances retention and drug delivery. These nanoparticles activate the STING pathway, stimulating dendritic cells and T cells to boost anti‐bladder cancer ...
Lei Peng, Anguo Zhao, Rongkang Li, Yujun Liu, Daitian Tang, Dashi Deng, Qi Zhuang, Rui Liang, Shaohua Zhang, Song Wu   +9 more
wiley   +1 more source

Cattle T2T X Chromosome: Insights into Natural Neocentromere Evolution

Low W, Pineda P, Macphillamy C, Ren Y, Chen T, Zhong L, Adelson D, Dessaix C, Perez-Silva J, Haggerty L, Martin F, Bottema C, Pitchford W, Rosen B, Smith T.   +14 more
europepmc   +1 more source

Sex-Biased Gene Expression and Evolution of the X Chromosome in Nematodes

Genetics, 2014
S. Albritton, Anna-Lena Kranz, P. Rao, M. Kramer, C. Dieterich, Sevinç Ercan   +5 more
semanticscholar   +1 more source

Plasmonic Molecular Entrapment for Label‐Free Methylated DNA Detection and Machine‐Learning Assisted Quantification

Advanced Science, EarlyView.
Plasmonic molecular entrapment (PME) is label‐free detection and quantification method for DNA methylation. This technique provides direct hotspot site generation around target analytes, overcoming mismatch geometrical properties. The PME demonstrates superior SERS performance and quantification capability, offering promising potential for epigenetic ...
Muhammad Shalahuddin Al Ja'farawy, Vo Thi Nhat Linh, Chaewon Mun, Jun‐Yeong Yang, Jun Young Kim, Rowoon Park, Sung‐Gyu Park, Dong‐Ho Kim, Min‐Young Lee, Ho Sang Jung   +9 more
wiley   +1 more source

Role of the X Chromosome in Alzheimer Disease Genetics.

JAMA Neurol
Belloy ME, Le Guen Y, Stewart I, Williams K, Herz J, Sherva R, Zhang R, Merritt V, Panizzon MS, Hauger RL, Gaziano JM, Logue M, Napolioni V, Greicius MD.   +13 more
europepmc   +1 more source

Neo-Sex Chromosome Evolution in Treehoppers Despite Long-Term X Chromosome Conservation. [PDF]

Genome Biol Evol
Palmer Droguett DH, Fletcher M, Alston BT, Kocher S, Cabral-de-Mello DC, Wright AE.   +5 more
europepmc   +1 more source

PP2A Promotes the Symmetric Division of MUC1‐Dominant Cancer Stem‐Like Cells in Small Cell Lung Cancer

Advanced Science, EarlyView.
During the G2/M phase, mucin1 (MUC1) activates protein phosphatase 2A (PP2A), leading to reduced phosphorylation of protein kinase C ζ (PKCζ) and NUMB, which promotes symmetric division and expansion of cancer stem‐like cells (CSLCs), thereby driving tumorigenesis. Combined inhibition of the MUC1–PP2A axis using LB100/GO203 with etoposide restores PKCζ
Shengze Li, Xinran Dong, Kexing Gao, Yiyang Wang, Min Li, Huayun Deng, Shuangyu Ma, Yaping Lv, Wei Jin, Quanfu Li, Yuming Wang, Xiaodong Liao, Kangjing Bian, Aiwu Zhou, Chengping Hu, Lei Huang   +15 more
wiley   +1 more source

The role of genetic testing in accurate diagnosis of X-linked sideroblastic anemia: novel ALAS2 mutations and the impact of X-chromosome inactivation. [PDF]

Sci Rep
Jové-Solavera D, Rámila M, Ferrer-Cortés X, Olivella M, Venturi V, Morado M, Hernández-Rodríguez I, Khan A, Pérez-Montero S, Tornador C, Germing U, Gattermann N, Sanchez M.   +12 more
europepmc   +1 more source