Results 301 to 310 of about 6,270,911 (362)

Microbial Biosensor for Sensing and Treatment of Intestinal Inflammation

Advanced Science, EarlyView.
The engineered calprotectin biosensor detects gut inflammation, processes the signal through genetic regulation, and responds by expressing the reporter sfGFP and the therapeutic protein secIL10. This dual functionality enables the engineered biosensor not only to sense but also to mitigate gut inflammation, highlighting its potential for disease ...
Duolong Zhu, Jeffrey Galley, Jason Pizzini, Elena Musteata, Martin V. Douglas, Walter J. Chazin, Eric P. Skaar, Jeffrey J. Tabor, Robert A. Britton   +8 more
wiley   +1 more source

Human Single-Cell RNA-Sequencing Data Supports the Hypothesis of X Chromosome Insensitivity but Is Ineffective in Testing the Dosage Compensation Model. [PDF]

Mol Biol Evol
Chen J, Chen X.
europepmc   +1 more source

MdDSK2a‐Like‐MdMTA Module Functions in Apple Cold Response via Regulating ROS Detoxification and Cell Wall Deposition

Advanced Science, EarlyView.
Under cold stress, MdDSK2a‐like is degraded via the 26S proteasome pathway, thereby alleviating the degradation of MdMTA induced by the 26S proteasome and autophagy pathways mediated by MdDSK2a‐like. The accumulated MdMTA increases the m6A levels of cold‐responsive genes, thereby contributing to increased ROS detoxification, deposition of cell wall, as
Nan Hou, Jieqiang He, Chana Bao, Fang Zhi, Xiaoxia Shen, Yu Liu, Chaoshuo Li, Tianle Fan, Xinyue Yang, Baohua Chu, Gege Qin, Zeyuan Liu, Chuang Mei, Bin Tan, Jiancan Feng, Fengwang Ma, Mickael Malnoy, Xuewei Li, Qingmei Guan   +18 more
wiley   +1 more source

Altered X-chromosome inactivation predisposes to autoimmunity. [PDF]

Sci Adv
Huret C, Ferrayé L, David A, Mohamed M, Valentin N, Charlotte F, Savignac M, Goodhardt M, Guéry JC, Rougeulle C, Morey C.   +10 more
europepmc   +1 more source

Imprinted X chromosome inactivation at the gamete-to-embryo transition. [PDF]

Mol Cell
Wei C, Kesner B, Yin H, Lee JT.
europepmc   +1 more source

Chasing shadows: Investigating X chromosome mediation in late-onset Alzheimer's disease. [PDF]

Adv Neurol (Singap)
Armon C, Cannon-Albright LA, Allen-Brady K, Wolfson S.   +3 more
europepmc   +1 more source

Modeling X chromosome inactivation using t5iLA naive human pluripotent stem cells. [PDF]

BMC Biol
Shang Y, Wang N, Wang H, An C, Sun W.
europepmc   +1 more source

X-chromosome-linked miR-542-5p as a key regulator of sex disparity in rats with adjuvant-induced arthritis by promoting Th17 differentiation. [PDF]

Biomark Res
Yang JJ, Li Z, Wang LN, Huang BX, Ng JPL, Xu XF, Wang YP, Zhang DW, Qin B, Zhang DQ, Liu C, Luo WD, Law BYK, Wang HM, Liu MH, Yun XY, Chan JTW, Wu WY, Li YT, Cheung PKF, Pou MC, Ha KS, Ao Ieong WF, Leong CH, Leong KI, Lei CW, Cheang LH, Wong VKW.   +27 more
europepmc   +1 more source

Histone variant macroH2A1 regulates synchronous firing of replication origins in the inactive X chromosome. [PDF]

Nucleic Acids Res
Arroyo M, Casas-Delucchi CS, Pabba MK, Prorok P, Pradhan SK, Rausch C, Lehmkuhl A, Maiser A, Buschbeck M, Pasque V, Bernstein E, Luck K, Cardoso MC.   +12 more
europepmc   +1 more source