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Recurrent CLTC::SYK fusions and CSF1R mutations in juvenile xanthogranuloma of soft tissue. [PDF]

Blood
Juvenile xanthogranuloma (JXG) is a histiocytic neoplasm that usually presents in the skin. Rarely, extracutaneous localizations occur; the genetic drivers of this clinical variant of JXG remain incompletely characterized.
P. Kemps, Hans J Baelde, R. Vorderman, Ellen Stelloo, Joost F Swennenhuis, K. Szuhai, M. Lamers, Boyd Kenkhuis, M. Al-Hussaini, I. B. Briaire-de Bruijn, S. W. Lam, J. Bovée, A. Cleven, R. M. Verdijk, C. V. van Noesel, Marijke van Dijk, M. Scheijde-Vermeulen, Annette H Bruggink, Jan Am van Laar, A. D. de Vries, W. Tissing, C. van den Bos, Andreas von Deimling, T. van Wezel, A.G.S. van Halteren, P.C.W. Hogendoorn   +25 more
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Dermoscopy of Juvenile Xanthogranuloma

Dermatology, 2020
Background: Dermoscopy is useful for the evaluation of juvenile xanthogranuloma (JXG). The classical “setting sun” pattern is characteristic of JXG, but its sensibility appears to be limited.
L. Peruilh-Bagolini, Mariana Silva-Astorga, M. J. Hernández San Martín, M. Manoli, C. Papageorgiou, Z. Apalla, A. Lallas   +6 more
semanticscholar   +4 more sources

Systemic juvenile xanthogranuloma: A systematic review

Pediatric Blood & Cancer, 2023
To perform a systematic review to investigate the available literature regarding systemic juvenile xanthogranuloma (SJXG) and report the population characteristics, clinical manifestation, therapy, and outcome.
Tong Zou, A. Wei, Hong-Hao Ma, H. Lian, Yali Liu, Dong Wang, Yunze Zhao, L. Cui, Zhigang Li, Rui Zhang, Tianyou Wang   +10 more
semanticscholar   +1 more source

Alectinib In the Treatment of Systemic Juvenile Xanthogranuloma of Infancy With ALK Translocation.

JAMA dermatology, 2023
This observational case series examines the diagnosis and treatment of 2 patients with systemic juvenile xanthogranuloma treated with alectinib.
Jiaosheng Xu, Xingfeng Yao, Yang Wen, Hongyun Lian, X. Han, Zigang Xu   +5 more
semanticscholar   +1 more source

Langerhans Cell Histiocytosis Evolving into Juvenile Xanthogranuloma: Two Linked Entities

American journal of dermatopathology, 2023
Background: Langerhans cell histiocytosis (LCH) represents a myeloid clonal proliferation that involves the skin and other organs. Occasionally, cases of LCH evolve into juvenile xanthogranuloma (JXG).
Nada Shaker, O. Sangueza
semanticscholar   +1 more source

Dermoscopy of juvenile xanthogranuloma: a retrospective descriptive study on 35 paediatric patients

Journal of the European Academy of Dermatology and Venereology, 2022
Juvenile xanthogranuloma (JXG) is a rare benign subtype of non-Langerhans cell histiocytosis. Dermoscopy is helpful in the diagnosis of JXG when presenting the typical dermoscopic features. The most characteristic dermoscopic aspect of the JXG is that of
E. D. Di Brizzi, E. Moscarella, C. Scharf, G. Argenziano, V. Piccolo   +4 more
semanticscholar   +1 more source

Dermatoscopy and clinicopathological correlation of juvenile xanthogranuloma in skin of colour: a series of six patients

Journal of the European Academy of Dermatology and Venereology, 2022
To the Editor, Juvenile xanthogranuloma (JXG) is a type of non-Langerhans cell histiocytosis characterized by benign proliferation of macrophages and dendritic cells.
P. Gupta, K. Vinay, A. Bishnoi, D. Chatterjee, S. Dogra   +4 more
semanticscholar   +1 more source

Juvenile Xanthogranuloma

Journal of Pediatric Ophthalmology & Strabismus, 1982
Juvenile xanthogranuloma (JXG) is a disease of unknown etiology and pathogenesis which was first recognized by dermatologists. The ocular complications provide the primary concern and notably affect the iris, producing spontaneous hemorrhages in the anterior chamber.
R D, Harley, N, Romayananda, G H, Chan
openaire   +2 more sources

Juvenile xanthogranuloma

Journal of the American Academy of Dermatology, 1997
Juvenile xanthogranuloma (JXG) is a benign, self-healing disorder characterized by solitary or multiple yellow-red nodules on the skin and, occasionally, in other organs. It is predominantly a disease of infancy or early childhood, although adults may also be affected.
A, Hernandez-Martin, E, Baselga, B A, Drolet, N B, Esterly   +3 more
openaire   +2 more sources

Disseminated Juvenile Xanthogranuloma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2006
SummaryJuvenile xanthogranuloma (JXG) is the most common type of non‐Langerhans cell histiocytosis occurring predominantly in infants and children. Typical lesions are asymptomatic red‐yellow papules and nodules on the scalp or in the axillae or groins. Multiple lesions are more common in children than in adults.
Gunter Haroske, Walter H.C. Burgdorf, Uwe Wollina   +2 more
openaire   +2 more sources