Complex Roles of Insect Cytochrome P450s in Chemical Adaptation. [PDF]
Chen QR, Moural TW, Zhu F.
europepmc +1 more source
Soy lecithin and DATEM, the two commonly used food emulsifiers introduced into many foods including peanut butter and puffed bread, in the 2000s, impair intestinal epithelial barrier integrity in human gut‐on‐a‐chip and induced pluripotent stem cell colon organoid models.
Duygu Yazici +22 more
wiley +1 more source
Identification of metabolic biomarkers and pathways associated with <i>Ichthyophonus hoferi</i> infection in White stumpnose (<i>Rhabdosargus globiceps</i>). [PDF]
Ndlovu IS +3 more
europepmc +1 more source
Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney +10 more
wiley +1 more source
Adenosine triphosphate-binding cassette transporters: key players in maintaining fetal health during pregnancy. [PDF]
Wang XH +9 more
europepmc +1 more source
Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells
MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe +5 more
wiley +1 more source
Gene model for the ortholog of <i>JhI-26</i> and a paralog in <i>Drosophila dunni</i>. [PDF]
Canard C, Chialvo P, Scott Chialvo C.
europepmc +1 more source
A lipid‐sensitive food choice behavior influences aging outcomes from a longevity‐promoting diet
C. elegans are exposed to a variety of bacteria in their natural environment and must be able to distinguish between beneficial and detrimental food sources. We show that C. elegans exposed to the bacterium from their natural habitat, Methylobacterium, disrupts lipid homeostasis, causing worms to avoid this bacterial species and choose the laboratory ...
Nicole L. Stuhr +4 more
wiley +1 more source
In a cytokine‐challenged human epidermal model, trans‐resveratrol reduces inflammation (IL‐1α) and oxidative stress markers (CYP1A1, CYP1B1), while modulating the expression of barrier‐related genes (LOR, OCLN) and differentiation‐associated CASP14. This supports its role as a multifunctional active for sensitive and compromised skin.
Irini M. Dijkhoff +6 more
wiley +1 more source
Evolution of Dermatophytic Fungi: Anthropogenic and Biogenic Environmental Factors
ABSTRACT Climate change presents new challenges to dermatologic care, ranging from anthropogenic factors, such as pollution that select for extremotolerant and potentially antifungal‐resistant fungi, to biogenic factors that can drive zoonotic outbreaks, which have received increased attention since the SARS‐CoV‐2 pandemic.
Aditya K. Gupta +2 more
wiley +1 more source

