Results 281 to 290 of about 149,321 (334)
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Chemical Metabolism of Xenobiotics by Gut Microbiota.
Current drug metabolism, 2020Among gut microbiota's newly explored roles in human biology is the ability to modify the chemical structures of foreign compounds (xenobiotics).
R. Nakov, T. Velikova
semanticscholar +1 more source
Pediatric Clinics of North America, 2001
Breastfeeding provides important benefits to mothers and infants and should be encouraged strongly as the optimal feeding choice for most infants. In assessing the effects of maternal medication on breastfeeding, clinicians must weigh the many benefits of breastfeeding for mothers and infants against the risk for exposing infants to a drug as it is ...
C R, Howard, R A, Lawrence
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Breastfeeding provides important benefits to mothers and infants and should be encouraged strongly as the optimal feeding choice for most infants. In assessing the effects of maternal medication on breastfeeding, clinicians must weigh the many benefits of breastfeeding for mothers and infants against the risk for exposing infants to a drug as it is ...
C R, Howard, R A, Lawrence
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Xenobiotic triglyceride formation
Xenobiotica, 19801. When 3-phenoxy[14C]benzoic acid was dosed orally (0.76 mg/kg) to rats, 1--3% of the administered radioactivity was found in the skin four days after dosing. Approximately 90% of this residue was unchanged 3-phenoxybenzoate, 10% was a neutral compound. 2. The residue in the skins of rats dosed with 193 mg of 3-phenoxybenzoic acid over 7 days (c.
J V, Crayford, D H, Hutson
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Clinica Chimica Acta, 1995
Nephrotoxicity can be grouped by the xenobiotics place of action, by the clinical presentation or by the generic toxic effect. The latter can be dose related, indirect, idiosyncratic or allergic. Nephrotoxicity of lithium, demeclocycline, aminoglycosides, cyclosporine, mercuric ion, nonsteroidal anti-inflammatory drugs, methoxyflurane, ethylene glycol,
M, Werner +3 more
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Nephrotoxicity can be grouped by the xenobiotics place of action, by the clinical presentation or by the generic toxic effect. The latter can be dose related, indirect, idiosyncratic or allergic. Nephrotoxicity of lithium, demeclocycline, aminoglycosides, cyclosporine, mercuric ion, nonsteroidal anti-inflammatory drugs, methoxyflurane, ethylene glycol,
M, Werner +3 more
openaire +2 more sources
Journal of Advancement in Medicine, 1998
The advances in medical technology during the last four decades has provided evidence for an underlying neurological basis for autism. The etiology for the variations of neurofunctional anomalies found in the autistic spectrum behaviors appears inconclusive as of this date but growing evidence supports the proposal that chronic exposure to toxic ...
S B, Edelson, D S, Cantor
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The advances in medical technology during the last four decades has provided evidence for an underlying neurological basis for autism. The etiology for the variations of neurofunctional anomalies found in the autistic spectrum behaviors appears inconclusive as of this date but growing evidence supports the proposal that chronic exposure to toxic ...
S B, Edelson, D S, Cantor
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Biliary Excretion of Xenobiotics
CRC Critical Reviews in Toxicology, 1975The biliary route is very important for the elimination of some foreign compounds from the body. For many of these compounds, an increase in the rate at which they are excreted into the bile will decrease their toxicity and vice versa. A number of factors which are known to alter the biliary excretion of xenobiotics, as well as the current concepts of ...
Curtis D. Klaassen, Gabriel L. Plaa
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Xenobiotic and Non-Xenobiotic Interventions in the Microbiome Therapeutics
Current Drug Metabolism, 2015It is now very much clear that the microbiome plays an important part in human health. Microbiome is associated with several diseases and targeting the whole microbiome is certainly a challenge before the scientists. The "Human Microbiome Project" is continually exploring certain therapeutic targets inside microbiome landscape that could be utilized ...
Vipin, Kumar +2 more
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Organophosphorus Xenobiotic Toxicology
Annual Review of Pharmacology and Toxicology, 2017Originally, organophosphorus (OP) toxicology consisted of acetylcholinesterase inhibition by insecticides and chemical threat agents acting as phosphorylating agents for serine in the catalytic triad, but this is no longer the case. Other serine hydrolases can be secondary OP targets, depending on the OP structure, and include neuropathy target ...
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The role of cytochrome P450-mediated detoxification in insect adaptation to xenobiotics.
Current Opinion in Insect Science, 2020K. Lu, Yuanyuan Song, R. Zeng
semanticscholar +1 more source
Nephrocarcinogenic xenobiotics
Toxicology Letters, 1990D, Henschler, W, Dekant
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