The TFIIH Subunit p89 (XPB) Localizes to the Centrosome during Mitosis
Cellular Oncology, 2010 Background: The general transcription factor II H (TFIIH), comprised of a core complex and an associated CAK-complex, functions in transcription, DNA repair and cell cycle control. Mutations of the two largest subunits, p89 (XPB) and p80 (XPD), cause the
Achim Weber +4 more
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Xeroderma pigmentosum. Case presentation.
Medisur, 2008 Twelve years old patient (YGS), female, white, of rural origin; with history of facial and truncal bullae since the age of eight months when exposed to the sun light. It was first diagnosed as solar dermatitis.
Damaris Díaz Leonard +2 more
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Xeroderma pigmentosum (case report)
Indian Journal of Ophthalmology, 1990 Xeroderma pigmentosum is a rare, hereditary and fatal disease of the skin. Ocular involvement is known to occur in 80% of cases. A case with typical cutaneous and ocular lesions is reported.
Dubey Arvind +4 more
doaj
Xeroderma Pigmentosum - A Family
Indian Journal of Dermatology, 2000 A family of xeroderma pigmentosum is reported. Four children of different ages were afflicted with varying clinical presentation. Sequential development and progression of the disease from freckling to malignancy within the family are discussed.
Garg Anush, Singhi M.K
doaj
Xeroderma pigmentosum group D 751 polymorphism as a predictive factor in resected gastric cancer treated with chemo-radiotherapy [PDF]
, 2006 AIM: To evaluate the potential association of xeroderma pigmentosum group D (XPD) codon 751 variant with outcome after chemo-radiotherapy in patients with resected gastric cancer.
Arias, F. (F.) +5 more
core
Immunochemical determination of an initial step in thymine dimer excision repair in xeroderma pigmentosum variant fibroblasts and biopsy material from the normal population and patients with basal cell carcinoma and melanoma [PDF]
, 2017 A monoclonal antibody specific for u.v.-induced thymine-thymine dimers in single-stranded DNA has been used in an enzyme immunoassay to investigate the loss of antigenicity associated with repair of this lesion in the first 2 h following 10 J/m2 254 nm ...
Boyle, John M. +2 more
core
Xeroderma Pigmentosum- Eye Changes
Indian Journal of Dermatology, 2002 Xeroderma pigmentosum is a rare hereditary and fatal disease of the skin. Ocular involvement is known to occur in 80% of cases. Two brothers of a family with cutaneous and ocular involvement are reported.
Bhaduri Gautam, Banerjee Anita
doaj
Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage [PDF]
, 1994 The rad2 mutant of Schizosaccharomyces pombe is sensitive to UV irradiation and deficient in the repair of UV damage. In addition, it has a very high degree of chromosome loss and/or nondisjunction.
Al-Harithy, R +6 more
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