Results 211 to 220 of about 46,793 (276)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Local and Symmetry-Resolved Electronic Structure of Liquid Dimethyl Sulfoxide from Resonant Inelastic Soft X-ray Scattering. [PDF]

J Phys Chem Lett
Weinhardt L, Hauschild D, Steininger R, Wansorra C, Yang W, Heske C.   +5 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Activating plasmonic catalysis through light-mediated steady-state spin modulation. [PDF]

Nat Commun
Hu X, Liu J, Zhu Z, Liu S, Wang L, Cheng J, Huang X, Li C, Feng K, Zhou Y, Xu Y, Feng Q, Zhang B, Chen X, Zhang L, Zhang Q, Wu B, Yin J, An X, Zhang XH, He L.   +20 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Probing the Local Environment in Potassium Salts and Potassium-Promoted Catalysts by Potassium Valence-to-Core X-ray Emission Spectroscopy. [PDF]

Inorg Chem
Rana A, Peredkov S, Behrens M, DeBeer S.
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Operando Characterization of Fe in Doped Ni_x(Fe_1-x)O_yH_z Catalysts for Electrochemical Oxygen Evolution. [PDF]

J Am Chem Soc
Halldin Stenlid J, Görlin M, Diaz-Morales O, Davies B, Grigorev V, Degerman D, Kalinko A, Börner M, Shipilin M, Bauer M, Gallo A, Abild-Pedersen F, Bajdich M, Nilsson A, Koroidov S.   +14 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Spin chemistry: the key to revolutionizing energy storage and conversion efficiency. [PDF]

Chem Sci
Zhang X, Pan J, Wan Y, Zheng X, Liu Y, Zhang Y, Liu X, Wei Q, Wu J, Iamprasertkun P, Wang B, Wu M, Hu H.   +12 more
europepmc   +1 more source