Results 1 to 10 of about 250 (83)

Lateral herniation during treatment with collagenase Clostridium histolyticum (Xiaflex) for Peyronie’s disease [PDF]

BMC Urology, 2021
Background Collagenase Clostridium histolyticum (CCH), also know as Xiaflex, with penile modeling is considered to be the gold standard non-surgical option for management of Peyronie’s disease and is known to be safe and efficacious.
Margaret K. Gannon, Amy M. Pearlman
doaj   +2 more sources

The Impact of Emerging Therapies and Declining Physician Reimbursement on Dupuytren Disease Treatment: A 21 Year Review [PDF]

Journal of Hand Surgery Global Online
Purpose: This study aimed to evaluate the trends in treatment and physician reimbursement for Dupuytren contracture (DC) within the Medicare population over a 21-year period, with a focus on how the introduction of collagenase Clostridium histolyticum ...
Evan H. Richman, MD, Dylan Rakowski, MD, Alexander Lauder, MD   +2 more
doaj   +2 more sources

Recent Pathophysiological Aspects of Peyronie’s Disease: Role of Free Radicals, Rationale, and Therapeutic Implications for Antioxidant Treatment—Literature Review

Advances in Urology, 2017
Peyronie’s disease (PD) is a chronic inflammation of tunica albuginea of the corpora cavernosa that causes an inelastic plaque resulting in penis deformation.
Gianni Paulis, Gennaro Romano, Luca Paulis, Davide Barletta   +3 more
doaj   +2 more sources

Late-Onset Penile Fracture After Collagenase <i>Clostridium histolyticum</i> Treatment for Peyronie's Disease in a 70-Year-Old Patient. [PDF]

Case Rep Urol
Collagenase Clostridium histolyticum (CCH) injections are the gold standard for nonsurgical management of Peyronie’s disease. While generally well tolerated, penis fracture is a known complication. Cases typically occur during intercourse in the weeks following treatment. Because of this, patients are advised to abstain from sexual activity for 4 weeks
Wainstein MD, Masih SE, Schuster TG.
europepmc   +2 more sources

Determining Risk Factors and Rate of Surgery After Collagenase Injections for Dupuytren Contracture [PDF]

Journal of Hand Surgery Global Online
Purpose: Collagenase injections are a nonsurgical treatment for Dupuytren contracture, but their long-term effectiveness in preventing surgery remains unclear. This study aimed to evaluate the rate of surgical intervention following collagenase treatment
Ryan C. Cha, BA, Juliet S. Chung, MD, Sina Ramtin, MD, Asif M. Ilyas, MD, MBA   +3 more
doaj   +2 more sources

Predictors of Pursuing Intralesional Xiaflex in Peyronie’s Disease Patients [PDF]

Journal of Sexual Medicine, 2021
Lawrence C Jenkins, Nahid Punjani, Carolyn Salter   +2 more
exaly   +2 more sources

Retraction: In Vitro Study of Novel Collagenase (XIAFLEX®) on Dupuytren's Disease Fibroblasts Displays Unique Drug Related Properties. [PDF]

PLoS ONE
PLOS One Editors
doaj   +2 more sources

Safety of Xiaflex® (Collagenase Clostridium histolyticum) Treatment for Adult Anterior Urethral Stricture Disease [PDF]

Cureus, 2023
Wiegand LR, Tran TQ, Heinsimer K, Shah B.   +3 more
exaly   +2 more sources

Real‐world effectiveness and safety of collagenase clostridium histolyticum‐aaes injections for the treatment of thigh cellulite in women: An open‐label study interim analysis

Journal of Cosmetic Dermatology, Volume 22, Issue 1, Page 177-185, January 2023., 2023
Abstract Background Collagenase clostridium histolyticum‐aaes (CCH‐aaes) is approved in the United States for moderate‐to‐severe cellulite in the buttocks of adult women. Aim Interim analysis to evaluate efficacy/safety of CCH‐aaes in the treatment of thigh cellulite. Methods Data were analyzed from a phase 3, open‐label study (REAL).
John H. Joseph, Steven H. Dayan, Ashish C. Bhatia, Sabrina G. Fabi, Sachin M. Shridharani, Lisa Donofrio, Jose R. Montes, Melanie D. Palm, Genzhou Liu, David Hernandez, Jill Edgecombe, Saji Vijayan, Deanne Mraz Robinson   +12 more
wiley   +1 more source

Vascular Necrosis of the Upper Extremity After Self-Treatment for Peyronie's Disease

Sexual Medicine, 2021
Peyronie's disease (PD) is associated with significant psychosocial distress, including anxiety, depression, and negative effects on interpersonal relationships.
David Yang, MD, Joshua Savage, PA-C, Tobias Köhler, MD, MPH, Sevann Helo, MD, Landon Trost, MD, Matthew Ziegelmann, MD   +5 more
doaj   +1 more source