Results 41 to 50 of about 18,387 (191)

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

Advanced Science, Volume 13, Issue 7, 3 February 2026.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu   +17 more
wiley   +1 more source

Scanner‐based real‐time automated volumetry reporting of the fetus, amniotic fluid, placenta, and umbilical cord for fetal MRI at 0.55T

Magnetic Resonance in Medicine, Volume 95, Issue 2, Page 975-986, February 2026.
Abstract Purpose This work aims to enable real‐time automated intra‐uterine volumetric reporting and fetal weight estimation for fetal MRI, deployed directly on the scanner. Methods A multi‐region segmentation nnUNet was trained on 146 images of 73 fetal subjects (coronal and axial orientations) for the parcellation of the fetal head, fetal body ...
Sara Neves Silva, Alena Uus, Hadi Waheed, Simi Bansal, Kamilah St Clair, Wendy Norman, Jordina Aviles Verdera, Daniel Cromb, Tomas Woodgate, Milou van Poppel, Johannes K. Steinweg, Jacqueline Matthew, Kuberan Pushparajah, David Lloyd, Vanessa Kyriakopoulou, Dimitris Siassakos, Anna David, Joseph V. Hajnal, Lisa Story, Mary A. Rutherford, Jana Hutter   +20 more
wiley   +1 more source

Cartesian MaxGIRF: Model‐based EPI reconstruction incorporating gradient nonlinearity and concomitant field effects

Magnetic Resonance in Medicine, Volume 95, Issue 2, Page 1044-1067, February 2026.
Abstract Purpose Lower field strength scanners with large bore size or complex geometries, and scanners with stronger gradient systems experience increased gradient nonlinearity and concomitant fields, each of which causes distortions in EPI. Current correction approaches based on image‐domain interpolation introduce undesirable spatial blurring.
Nam G. Lee, Sophia X. Cui, Krishna S. Nayak   +2 more
wiley   +1 more source

How Smart is your Android Smartphone? [PDF]

, 2010
Smart phones are ubiquitous today. These phones generally have access to sensitive personal information and, consequently, they are a prime target for attackers.
Mulani, Deepika
core   +3 more sources

On Secure Implementation of an IHE XUA-Based Protocol for Authenticating Healthcare Professionals [PDF]

, 2009
The importance of the Electronic Health Record (EHR) has been addressed in recent years by governments and institutions.Many large scale projects have been funded with the aim to allow healthcare professionals to consult patients data. Properties such as
A. Armando, A. Armando, A. Fantechi, A. Lapadula, D. Dolev, G. Lowe, K. Bhargavan, M. Beek ter, P. Broadfoot, S. Hansen, T. Groß   +10 more
core   +1 more source

Associating protein residues in the literature with structural data

Acta Crystallographica Section D, Volume 82, Issue 2, Page 113-125, February 2026.
A software tool is introduced for associating text mentions of protein residues with their respective residues in a protein structure, with display in a molecular viewer.Protein structures are crucial in understanding the function, mechanism and disease‐causing variants of proteins within any living cell.
Melanie Vollmar, Simon Westrip, Sreenath Nair, Balakumaran Balasubramaniyan, Sameer Velankar, Louise Jones, Peter Strickland   +6 more
wiley   +1 more source

Reviewing seas of data: Integrating image‐based bio‐logging and artificial intelligence to enhance marine conservation

Methods in Ecology and Evolution, Volume 17, Issue 2, Page 272-290, February 2026.
Abstract Conservation of marine ecosystems can be improved through a better understanding of ecosystem functioning, particularly the cryptic underwater behaviours and interactions of marine predators. Image‐based bio‐logging devices (including images, videos and active acoustic) are increasingly used to monitor wildlife movements, foraging behaviours ...
Marianna Chimienti, Akiko Kato, Vahid Seydi, Stefan Schoombie, Jefferson T. Hinke, Ruth Joy, Damian C. Lidgard, W. Chris Oosthuizen, Yannis P. Papastamatiou, Yan Ropert‐Coudert, Akinori Takahashi, Jean‐Baptiste Thiebot, Muriel Visani, Mickael Coustaty, Tiphaine Jeanniard‐du‐Dot   +14 more
wiley   +1 more source

Phylogenetic reconciliation provides new insights into the evolutionary diversification of the glutamine synthetase gene family in seed plants

The FEBS Journal, Volume 293, Issue 3, Page 859-877, February 2026.
Phylogenetic analyses of glutamine synthetase (GS) in seed plants revealed that all three major evolutionary lineages (GS2, GS1a, and GS1b) must have been present in the common ancestor, with GS2 being the first lineage to diverge. Unlike GS1b, GS1a and GS2 are usually single‐copy genes, even though they underwent duplications that resulted in ...
Elena Aledo, Rafael Antonio Cañas, Francisco R. Cantón, Juan Carlos Aledo   +3 more
wiley   +1 more source

Neuromorphic Visual Receptive Field Hardware with Vertically Integrated Indium‐Gallium‐Zinc‐Oxide Optoelectronic Memristors over Silicon Neuron Transistors

Advanced Materials, Volume 38, Issue 3, 13 January 2026.
This work proposes neuromorphic visual receptive field hardware with vertically integrated amorphous In‐Ga‐Zn‐O optoelectronic memristors and Si neuron transistors for retina‐inspired visual processing. The visual receptive field array, comprising ON‐ and OFF‐type cells, facilitates edge detection, thereby enhancing perception in complex images, such ...
Hyun Wook Kim, Jin Hong Kim, Dong Hoon Shin, Min Chung Jung, Tae Won Park, Hyung Jun Park, Joon‐Kyu Han, Cheol Seong Hwang   +7 more
wiley   +1 more source

Bernard‐Soulier Syndrome: Identification of a Novel GP1BB Variant in a Mauritanian Patient

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
This study identifies a new mutation of the GP1BB gene responsible for Bernard‐Soulier syndrome in a Mauritanian patient. Genetic analysis reveals a nucleotide duplication resulting in a severe platelet adhesion defect. This work highlights the importance of molecular diagnosis and therapeutic strategies to improve the management of affected patients ...
Mohamed Lemine Salem, Ektelbenina Zein, Ghaber Sidi Mohamed   +2 more
wiley   +1 more source