XMRV: usage of receptors and potential co-receptors [PDF]
Background XMRV is a gammaretrovirus first identified in prostate tissues of Prostate Cancer (PC) patients and later in the blood cells of patients with Chronic Fatigue Syndrome (CFS).
Gaddam Durga+8 more
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Absence of XMRV and closely related viruses in primary prostate cancer tissues used to derive the XMRV-infected cell line 22Rv1. [PDF]
The 22Rv1 cell line is widely used for prostate cancer research and other studies throughout the world. These cells were established from a human prostate tumor, CWR22, that was serially passaged in nude mice and selected for androgen independence.
Jaydip Das Gupta+7 more
doaj +5 more sources
In 2009, Lombardi et al. reported their startling finding that the gammaretrovirus xenotropic murine leukemia virus-related retrovirus (XMRV) is present in 67% of blood samples of patients suffering from chronic fatigue syndrome (CFS), as opposed to only
Brendan Oakes+4 more
doaj +2 more sources
Of Mice and Men: On the Origin of XMRV [PDF]
The novel human retrovirus xenotropic murine leukemia virus-related virus (XMRV) is arguably the most controversial virus of this moment. After its original discovery in prostate cancer tissue from North American patients, it was subsequently detected in individuals with chronic fatigue syndrome from the same continent.
Antoinette C. van der Kuyl+2 more
openalex +5 more sources
Lack of detection of XMRV in seminal plasma from HIV-1 infected men in The Netherlands.
BackgroundXenotropic murine leukaemia virus-related virus (XMRV) is a recently discovered human gammaretrovirus with yet unknown prevalence and transmission route(s).
Marion Cornelissen+8 more
doaj +3 more sources
An XMRV Derived Retroviral Vector as a Tool for Gene Transfer [PDF]
AbstractBackgroundRetroviral vectors are widely used tools for gene delivery and gene therapy. They are useful for gene expression studies and genetic manipulationin vitroandin vivo. Many retroviral vectors are derived from the mouse gammaretrovirus, murine leukemia virus (MLV). These vectors have been widely used in gene therapy clinical trials. XMRV,
Daniel Cervantes‐García+2 more
openalex +9 more sources
Ductal variant of prostate adenocarcinoma harbor Xenotropic murine leukemia virus related virus (XMRV) infection: a novel finding in subtype of prostate cancer. [PDF]
Baig FA+4 more
europepmc +3 more sources
No evidence for XMRV nucleic acids, infectious virus or anti-XMRV antibodies in Canadian patients with chronic fatigue syndrome. [PDF]
The gammaretroviruses xenotropic murine leukemia virus (MLV)-related virus (XMRV) and MLV have been reported to be more prevalent in plasma and peripheral blood mononuclear cells of chronic fatigue syndrome (CFS) patients than in healthy controls.
Imke Steffen+16 more
doaj +5 more sources
XMRV as a Human Pathogen? [PDF]
Xenotropic murine leukemia virus-related virus (XMRV) has been proposed to be associated with prostate cancer and chronic fatigue syndrome (CFS). This proposition has been controversial because many investigators have failed to replicate the reported associations.
Mark A. Wainberg, Kuan‐Teh Jeang
openalex +3 more sources
Is XMRV a causal virus for prostate cancer? [PDF]
The potential association between xenotropic murine leukaemia virus-related gammaretrovirus (XMRV) and prostate cancer (PCa) has been documented since 2006. It is important for furthering our understanding of the biological mechanisms of PCa to ascertain whether this association is causal.
Zhenzhen Zhang+4 more
openalex +4 more sources