What is XMRV and should we be worried about it? [PDF]
Transfusion, 2011 Hua Shan
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XMRV and prostate cancer—a 'final' perspective [PDF]
Nature Reviews Urology, 2012 XMRV was first described in 2006, when it was identified in samples isolated from prostate cancer tissues. However, studies have since shown that XMRV arose in the laboratory and was formed by genetic recombination between two viral genomes carried in the germline DNA of mice used during serial transplantation of the CWR22 prostate cancer xenograft ...
Karen S. Sfanos +3 more
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Paclitaxel: Application in Modern Oncology and Nanomedicine‐Based Cancer Therapy
Oxidative Medicine and Cellular Longevity, Volume 2021, Issue 1, 2021., 2021 Paclitaxel is a broad‐spectrum anticancer compound, which was derived mainly from a medicinal plant, in particular, from the bark of the yew tree Taxus brevifolia Nutt. It is a representative of a class of diterpene taxanes, which are nowadays used as the most common chemotherapeutic agent against many forms of cancer.
Javad Sharifi-Rad +24 more
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Mechanism for XMRV neurotoxicity [PDF]
Retrovirology, 2011 Xenotropic murine leukemia virus-related virus (XMRV) has been found in a high percentage of humans with chronic fatigue syndrome (CFS). However, more recent studies have failed to confirm these results, and it now appears likely that the original findings were due to patient sample contamination. Because it initially appeared that XMRV was involved in
Ramona Aranda +4 more
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Xenotropic murine leukemia virus–related virus (XMRV) and blood transfusion: report of the AABB interorganizational XMRV task force [PDF]
, 2011 n ...
Harvey G. Klein +7 more
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In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer. [PDF]
PLoS ONE, 2012 XMRV, or xenotropic murine leukemia virus (MLV)-related virus, is a novel gammaretrovirus originally identified in studies that analyzed tissue from prostate cancer patients in 2006 and blood from patients with chronic fatigue syndrome (CFS) in 2009 ...
Deanna Lee +18 more
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XMRV replicates preferentially in mucosal sites in vivo: Relevance to XMRV transmission? [PDF]
Retrovirology, 2011 Xenotropic Murine Leukemia Virus-related Retrovirus (XMRV) was identified from prostate cancer tissue using DNA based ViroChip technology as well as in a cohort of chronic fatigue syndrome patients. To delineate the infection dynamics and dissemination in vivo, we have thus far infected 7 healthy rhesus macaques and 2 pigtailed macaques.
Kenneth A. Rogers +12 more
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Antibody responses against xenotropic murine leukemia virus-related virus envelope in a murine model. [PDF]
PLoS ONE, 2011 Xenotropic murine leukemia virus-related virus (XMRV) was recently discovered to be the first human gammaretrovirus that is associated with chronic fatigue syndrome and prostate cancer (PC).
Natalia Makarova +14 more
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No detection of XMRV in blood samples and tissue sections from prostate cancer patients in Northern Europe. [PDF]
PLoS ONE, 2011 BACKGROUND: We recently published the rare detection of xenotropic murine leukemia virus-related virus (XMRV) (1/105) in prostate cancer (PCA) tissue of patients in Northern Europe by PCR.
Kristin Stieler +8 more
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Immune correlates of XMRV infection [PDF]
Retrovirology, 2011 Methods This hypothesis was addressed by multiplex profiling of plasma cytokines and chemokines on a LuminexTM platform and phenotypic analysis of leukocyte subsets by multi-parameter flow cytometry in XMRV infected CFS patients versus uninfected controls. XMRV-infected subject and control samples were assayed blindly.
Max A. Pfost +4 more
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