Results 51 to 60 of about 1,109 (182)
Complex Codon Usage Pattern and Compositional Features of Retroviruses
Computational and Mathematical Methods in Medicine, Volume 2013, Issue 1, 2013., 2013 Retroviruses infect a wide range of organisms including humans. Among them, HIV‐1, which causes AIDS, has now become a major threat for world health. Some of these viruses are also potential gene transfer vectors. In this study, the patterns of synonymous codon usage in retroviruses have been studied through multivariate statistical methods on ORFs ...
Sourav RoyChoudhury +2 more
wiley +1 more source
No biological evidence of XMRV infection in cervical smears from HIV/ HPV positive and negative Kenyan women. [PDF]
PLoS ONE, 2012 BACKGROUND: XMRV (xenotropic murine leukaemia virus-related virus) is a gammaretrovirus first discovered in human prostate carcinomas and later linked to chronic fatigue syndrome (CFS).
Xiaotong He +5 more
doaj +1 more source
Journal of Pathogens, Volume 2013, Issue 1, 2013., 2013 Toxoplasma gondii is not only implicated in schizophrenia and related disorders, but also in Alzheimer′s or Parkinson′s disease, cancer, cardiac myopathies, and autoimmune disorders. During its life cycle, the pathogen interacts with ~3000 host genes or proteins.
C. J. Carter, Cormac G. M. Gahan
wiley +1 more source
Mouse DNA contamination in human tissue tested for XMRV [PDF]
Retrovirology, 2010 Abstract Background We used a PCR-based approach to study the prevalence of genetic sequences related to a gammaretrovirus, xenotropic murine leukemia virus-related virus, XMRV, in human prostate cancer. This virus has been identified in the US in prostate cancer patients and in those with chronic fatigue syndrome ...
Robinson, M +10 more
openaire +6 more sources
Probing Retroviral and Retrotransposon Genome Structures: The “SHAPE” of Things to Come
Molecular Biology International, Volume 2012, Issue 1, 2012., 2012 Understanding the nuances of RNA structure as they pertain to biological function remains a formidable challenge for retrovirus research and development of RNA‐based therapeutics, an area of particular importance with respect to combating HIV infection.
Joanna Sztuba-Solinska +2 more
wiley +1 more source
Specific Roles of MicroRNAs in Their Interactions with Environmental Factors
Journal of Nucleic Acids, Volume 2012, Issue 1, 2012., 2012 MicroRNAs (miRNAs) have emerged as critical regulators of gene expression by modulating numerous target mRNAs expression at posttranscriptional level. Extensive studies have shown that miRNAs are critical in various important biological processes, including cell growth, proliferation, differentiation, development, and apoptosis.
Juan Wang, Qinghua Cui, Kenneth K. W. To
wiley +1 more source
XMRV—contaminant, not cause? [PDF]
Nature Reviews Urology, 2011 Doubts about the association between xenotropic murine leukemia virus-related virus (XMRV) and prostatic malignancy have been lent great weight by several recently published papers. The new evidence indicates that XMRV is an artifact generated during production of prostate cancer cell lines.
openaire +2 more sources
Absence of detectable XMRV and other MLV-related viruses in healthy blood donors in the United States. [PDF]
PLoS ONE, 2011 BACKGROUND: Preliminary studies in chronic fatigue syndrome (CFS) patients and XMRV infected animals demonstrated plasma viremia and infection of blood cells with XMRV, indicating the potential risk for transfusion transmission.
Shixing Tang +8 more
doaj +1 more source
Risk‐Reduction Strategies for Platelet Transfusion in the United States
The Scientific World Journal, Volume 11, Issue 1, Page 624-640, 2011., 2011 Despite bacterial culture of platelets, transfusion‐associated bacteremia/sepsis (TABS) may occur with a frequency of approximately 1/60,000 platelet transfusions, while an emerging transfusion‐transmitted infection (TTI) could reproduce the epidemic of transfusion‐transmitted human immunodeficiency virus (HIV) in the future.
Eleftherios C. Vamvakas, Edward J. Benz
wiley +1 more source
The effects of XMRV gene expression on the mouse prostate [PDF]
Retrovirology, 2011 Xenotropic murine leukemia virus related virus (XMRV) has been the subject of intense investigation since its discovery and initial characterization in human prostate carcinoma. Notwithstanding the important and ongoing controversies surrounding detection methods, seroprevalence, disease association, or viral origin, we sought to determine whether XMRV
Rauch, Daniel +3 more
openaire +3 more sources