Results 71 to 80 of about 1,109 (182)
The Strong Protective Effect of Circumcision against Cancer of the Penis
Male circumcision protects against cancer of the penis, the invasive form of which is a devastating disease confined almost exclusively to uncircumcised men. Major etiological factors are phimosis, balanitis, and high‐risk types of human papillomavirus (HPV), which are more prevalent in the glans penis and coronal sulcus covered by the foreskin, as ...
Brian J. Morris+7 more
wiley +1 more source
MoMuLV‐ts‐1: A Unique Mouse Model of Retrovirus‐Induced Lymphoma Transmitted by Breast Milk
Our laboratory has developed a murine model of lymphoma via breast milk transmission of MoMuLV‐ts‐1 (Moloney murine leukemia virus‐temperature sensitive mutant‐1). Uninfected offspring suckled from infected surrogate mothers become infected and develop lymphoma.
J. Chakraborty+4 more
wiley +1 more source
Prevalence of XMRV in blood donors, HTLV and HIV cohorts [PDF]
Background PCR-based testing has been widely utilized to assess the prevalence of Xenotropic Murine Leukemia Virus-related Virus (XMRV) in prostate cancer and chronic fatigue syndrome patients. An alternative approach, screening for antibodies elicited by XMRV infection, represents a more desirable option for large-scale epidemiologic studies.
Gregor Leckie+6 more
openaire +2 more sources
Susceptibility of human lymphoid tissue cultured ex vivo to xenotropic murine leukemia virus-related virus (XMRV) infection. [PDF]
BackgroundXenotropic murine leukemia virus-related virus (XMRV) was generated after a recombination event between two endogenous murine leukemia viruses during the production of a prostate cancer cell line. Although the associations of the XMRV infection
Marta Curriu+12 more
doaj +1 more source
Mouse "xenotropic" gammaretroviruses, XMRV and their XPR1 receptor [PDF]
Background Xenotropic/polytropic mouse leukemia viruses (XPMLVs) and the xenotropic murine leukemia virusrelated virus (XMRV) identified in human patient samples rely on the XPR1 receptor for entry into cells. There are 5 functional variants of Xpr1 in Mus species and laboratory mouse strains that differ in their ability to support entry of XMRV and ...
Qingping Liu+6 more
openaire +3 more sources
Background A novel gammaretrovirus named xenotropic murine leukemia virus-related virus (XMRV) has been recently identified and found to have a prevalence of 40% in prostate tumor samples from American patients carrying a homozygous R462Q mutation in the
Miller Kurt+8 more
doaj +1 more source
Recombinant origin, contamination, and de-discovery of XMRV [PDF]
The discovery and de-discovery of the xenotropic murine leukemia virus-related virus (XMRV) has been a tumultuous roller-coaster ride for scientists and patients. The initial associations of XMRV with chronic fatigue syndrome and prostate cancer, while providing much hope and optimism, have now been discredited and/or retracted following overwhelming ...
Krista A. Delviks-Frankenberry+3 more
openaire +3 more sources
Background The involvement of xenotropic murine leukemia virus-related virus (XMRV) in prostate cancer (PC) and chronic fatigue syndrome (CFS) is disputed as its reported prevalence ranges from 0% to 25% in PC cases and from 0% to more than 80% in CFS ...
Sakuma Ryuta+11 more
doaj +1 more source
No evidence for the involvement of XMRV or MCV in the pathogenesis of breast cancer [PDF]
The aetiology of breast cancer remains elusive. A viral aetiology has been proposed, but to date no virus has been conclusively demonstrated to be involved. Recently, two new viruses, namely Merkel cell polyomavirus (MCV) and xenotropic murine leukaemia virus-related virus (XMRV) have been identified and implicated in the pathogenesis of Merkel cell ...
K M I Al Zarouni+3 more
openaire +3 more sources
DNA extraction columns contaminated with murine sequences. [PDF]
Sequences of the novel gammaretrovirus, xenotropic murine leukemia virus-related virus (XMRV) have been described in human prostate cancer tissue, although the amounts of DNA are low. Furthermore, XMRV sequences and polytropic (p) murine leukemia viruses
Otto Erlwein+5 more
doaj +1 more source