Results 71 to 80 of about 2,300 (209)
Testing Strategies for Detection of Xenotropic Murine Leukemia Virus‐Related Virus Infection
Advances in Virology, Volume 2011, Issue 1, 2011., 2011 Xenotropic murine leukemia virus‐related virus (XMRV) is a newly identified gamma retrovirus and may be associated with prostate cancer‐ (PC) and chronic fatigue syndrome (CFS). Since its identification in 2006 and detection of polytropic murine lenkemia virus (MLV)‐like sequences in CFS patients in 2010, several test methods including nucleic acid ...
Shixing Tang +2 more
wiley +1 more source
Recombinant origin, contamination, and de-discovery of XMRV [PDF]
Current Opinion in Virology, 2012 The discovery and de-discovery of the xenotropic murine leukemia virus-related virus (XMRV) has been a tumultuous roller-coaster ride for scientists and patients. The initial associations of XMRV with chronic fatigue syndrome and prostate cancer, while providing much hope and optimism, have now been discredited and/or retracted following overwhelming ...
Krista, Delviks-Frankenberry +3 more
openaire +2 more sources
No association of xenotropic murine leukemia virus-related viruses with prostate cancer. [PDF]
PLoS ONE, 2011 BACKGROUND: The association of the xenotropic murine leukemia virus-related virus (XMRV) with prostate cancer continues to receive heightened attention as studies report discrepant XMRV prevalences ranging from zero up to 23%.
William M Switzer +4 more
doaj +1 more source
Interaction between herpesvirus entry mediator and HSV-2 glycoproteins mediates HIV-1 entry of HSV-2-infected epithelial cells. [PDF]
, 2017 Herpes simplex virus type 2 (HSV-2) increases human immunodeficiency virus type 1 (HIV-1) acquisition and transmission via unclear mechanisms. Herpesvirus entry mediator (HVEM), an HSV-2 entry receptor, is highly expressed on HIV-1 target cells (CD4+ T ...
He, S +6 more
core +1 more source
Key determinants of target DNA recognition by retroviral intasomes [PDF]
, 2015 BACKGROUND: Retroviral integration favors weakly conserved palindrome sequences at the sites of viral DNA joining and generates a short (4–6 bp) duplication of host DNA flanking the provirus.
Ballandras-Colas, A +4 more
core +2 more sources
Murine Leukemia Viruses: Objects and Organisms
Advances in Virology, Volume 2011, Issue 1, 2011., 2011 Murine leukemia viruses (MLVs) are among the simplest retroviruses. Prototypical gammaretroviruses encode only the three polyproteins that will be used in the assembly of progeny virus particles. These are the Gag polyprotein, which is the structural protein of a retrovirus particle, the Pol protein, comprising the three retroviral enzymes—protease ...
Alan Rein, Arifa S. Khan
wiley +1 more source
Mouse DNA contamination in human tissue tested for XMRV [PDF]
Retrovirology, 2010 Abstract Background We used a PCR-based approach to study the prevalence of genetic sequences related to a gammaretrovirus, xenotropic murine leukemia virus-related virus, XMRV, in human prostate cancer. This virus has been identified in the US in prostate cancer patients and in those with chronic fatigue syndrome ...
Robinson, M +10 more
openaire +5 more sources
Protease Cleavage Leads to Formation of Mature Trimer Interface in HIV-1 Capsid [PDF]
, 2012 During retrovirus particle maturation, the assembled Gag polyprotein is cleaved by the viral protease into matrix (MA), capsid (CA), and nucleocapsid (NC) proteins.
Angela M. Gronenborn +10 more
core +4 more sources
Dynein Regulators Are Important for Ecotropic Murine Leukemia Virus Infection [PDF]
, 2016 Indexación: Web of Science.During the early steps of infection, retroviruses must direct the movement of the viral genome into the nucleus to complete their replication cycle.
Arriagada, Gloria +4 more
core +1 more source
Of Mice and Men: On the Origin of XMRV [PDF]
Frontiers in Microbiology, 2011 The novel human retrovirus xenotropic murine leukemia virus-related virus (XMRV) is arguably the most controversial virus of this moment. After its original discovery in prostate cancer tissue from North American patients, it was subsequently detected in individuals with chronic fatigue syndrome from the same continent.
van der Kuyl, Antoinette Cornelia +2 more
openaire +4 more sources