A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng +16 more
wiley +1 more source
Characterization of C16-C36 alkane degradation and oily sludge bioremediation by <i>Rhodococcus erythropolis</i> XP. [PDF]
Zhang Y +7 more
europepmc +1 more source
A conditional multi‐task deep learning framework is developed for designing and optimizing Full‐Stokes Hyperspectro‐Polarimetric Encoding Metasurfaces (FHPEMs). This framework achieves joint spectro‐polarimetric learning and unified forward–inverse design.
Chenjie Gong +9 more
wiley +1 more source
Expanding the landscape of nucleotide excision repair disorders: from discovery to therapy. [PDF]
Theil AF, Hoeijmakers JH.
europepmc +1 more source
GPX4 Inhibitor Resistance and Metastatic Features in Triple‐Negative Breast Cancer
This study establishes breast cancer cell lines that are resistant to glutathione peroxidase 4 inhibitors (GPX4i) in vitro and investigates the metastatic capacity of the GPX4i‐resistant versus parental lines in vivo. GPX4i‐resistant cells survive upon intravenous injection, but lose capacity to spontaneously metastasize.
Marie Sabatier +16 more
wiley +1 more source
Polymorphisms and Expression Characteristics of the ZSWIM7 Gene Are Associated with the Fertility of Male Allotetraploid of Red Crucian Carp × Common Carp. [PDF]
Dai T +5 more
europepmc +1 more source
Additive and Partially Dominant Effects from Genomic Variation Contribute to Rice Heterosis
Additive and partially dominant effects, namely at mid‐parent levels or values between mid‐parent and parental levels, respectively, are the predominant inheritance patterns of heterosis‐associated molecules. These two genetic effects contribute to heterosis of agronomic traits in both rice and maize, as well as biomass heterosis in Arabidopsis ...
Zhiwu Dan +8 more
wiley +1 more source
A Large and Precise All-Sky Photometric Standard Star Dataset Across More Than 200 Passbands. [PDF]
Xiao K +14 more
europepmc +1 more source
Multi‐Tissue Omics Analysis Uncovers Translational Regulation Underlying Complex Traits in Pigs
Integrated multi‐omics across pig breeds and tissues reveals key principles of post‐transcriptional translational regulation and their contribution to trait formation. A gene network framework integrating transcriptomic and translatomic data is developed and applied to elucidate the genetic basis of meat production, offering new insights into mammalian
Chao Wang +13 more
wiley +1 more source
Efficacy of phytochemicals derived from Artocarpus heterophyllus (Jackfruit) as inhibitors against NS2B/NS3 protease of dengue virus: an in-silico investigation. [PDF]
Uddin MAR +10 more
europepmc +1 more source

