Results 161 to 170 of about 618,994 (277)

Methyl on the Bridge: 2‐Methyl Propellane as Precursor for 1,3‐Substituted 2‐Methylated Bicyclo[1.1.1]Pentanes

Chemistry – A European Journal, EarlyView.
The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve, Mariana Gomes Manso, Tibo Van Eeckhoorn, Mark E. Light, Bruno Linclau   +4 more
wiley   +1 more source

The bHLHzip-type transcription factor, <i>MaHpa3</i>, regulates conidial rodlet formation and cell surface hydrophobicity in the insect fungal pathogen <i>Metarhizium acridum</i>. [PDF]

Virulence
Song D, Yan X, Xie S, Guo G, Cao Y, Xia Y.   +5 more
europepmc   +1 more source

Preparing an Exsolvable Ru‐Substituted LaFeO3 Perovskite With High Surface Area From a Self‐Sacrificial Polymer Template: A Versatile Strategy for Enhanced Catalytic Performance

Chemistry – A European Journal, EarlyView.
High‐surface‐area LaFe0.9Ru0.1O3 is prepared by infiltration of porous Amberlite XAD16 polymer beads. Ru exsolution of this perovskite material leads to a supported catalyst with small Ru particles, exhibiting promising catalytic performance propane combustion.
Jaime Gallego, Yu Wang, Alexander Santamaría, Herbert Over, Bernd M. Smarsly   +4 more
wiley   +1 more source

Knuckle, Knuckle, Dimple, Dimple: Do Not Miss A Diagnostic Opportunity. [PDF]

Clin Case Rep
Pellegrin MC, Tamaro G, Fachin A, Barbi E, Tornese G.   +4 more
europepmc   +1 more source

Spouted bed drying parameters and adjuvant effects on polyphenol retention and antioxidant activity in mango peel powders

The Canadian Journal of Chemical Engineering, EarlyView.
Spouted bed drying of mango peels with colloidal SiO2 and corn starch produces a free‐flowing powder with reduced agglomeration, increased drying yield, and preserved antioxidant and polyphenol content. Abstract The production of polyphenol‐rich powders is a promising strategy for valorizing agro‐industrial byproducts. This study evaluated drying yield,
Guilherme Henrique Alves Pinto, Fábio Bentes Freire, José Teixeira Freire, Wanderley Pereira Oliveira   +3 more
wiley   +1 more source

Effect of Different Chemo-Mechanical Shaping Protocols on the Intratubular Penetration of a Bioceramic Sealer. [PDF]

J Clin Med
Generali L, Veneri F, Gaeta C, Cavani F, Ambu E, Bertucci S, Vallotto G, Filippini T, Pedullà E.   +8 more
europepmc   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Rare internal malignancies in xeroderma pigmentosum: A report of two cases from Tunisia and analysis of driver mutations. [PDF]

Cancer Pathog Ther
Rammeh S, Ben Taher Y, Ben Rekaya M, Ben Rejeb S, Lahmar A, Jones M, Zeglaoui F, Belguith N.   +7 more
europepmc   +1 more source

Is a Clinical Trial With a Non‐Bioequivalent Batch Necessary? The Critical Role of Intrasubject Variability in Olaparib Formulation Bridging by PBPK

Clinical Pharmacology &Therapeutics, EarlyView.
Although physiologically based pharmacokinetic (PBPK) modeling is increasingly being used to support oral drug formulation bridging, the acceptance by regulatory agencies is low. One of the primary concerns is the absence of clinical pharmacokinetic (PK) data from a non‐bioequivalent (non‐BE) batch during model validation.
Jin Dong, Andrea Moir, Xavier Pepin, Elizabeth Lowe, Sandy Hopkins, Weifeng Tang, Diansong Zhou   +6 more
wiley   +1 more source

Antibody Deficiency in Xeroderma Pigmentosum. [PDF]

J Clin Immunol
Rossmanith R, Geier CB, Gruber RW, Wolf HM.   +3 more
europepmc   +1 more source