Results 31 to 40 of about 184,467 (306)

Alternative Rapid Methods for Coverslip Removal: A Comparative Study [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: In 21st century, the focus is to develop method which yields outcome in shorter tenure, and are rapid, safe and obtain quicker results.
Mahesh H Karigoudar, Sachin Shivaji Kapse, Disha B Shankar, Shikha Sharma, Divya Prafulla Yerraguntla   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Optimising sample preparation to enhance contrast-to-noise ratio in X-ray phase contrast tomography white matter (WM) imaging of the central nervous system

Frontiers in Physics
The choice of fixative is critical in X-ray phase-contrast tomography (XPCT) because it affects tissue preservation, contrast enhancement and compatibility with other imaging techniques.
Michela Fratini, Michela Fratini, Lorenzo Massimi, Francesco Brun, Darren Batey, Inna Bukreeva, Alberto Mittone, Alberto Bravin, Elena Longo, Giuliana Tromba, Federico Giove, Federico Giove, Silvia Cipiccia, Alejandra Sierra   +13 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Supporting information for Abraham model correlations for solute partitioning into o-xylene, m-xylene and p-xylene from both water and the gas phase [PDF]

, 2011
This document includes supporting information and figures for an article on the Abraham model correlations for solute partitioning into o-xylene, m-xylene and p-xylene from both water and the gas ...
De la Rosa, Nohelli E., Abraham, M. H. (Michael H.), Stephens, Timothy W., Ye, Shulin, Quay, Amanda N., Saifullah, Mariam, Chou, Vicky, Acree, William E. (William Eugene)   +7 more
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Layer‐by‐Layer Processed Organic Photovoltaic Cells Using Slot‐Die‐Coating Methods and Non‐halogenated Solvents under Ambient Conditions with PCE of 10%

Advanced Materials Interfaces, 2023
Laboratory‐controlled conditions, spin‐coating method, and non‐ecofriendly halogenated solvents that have been employed for higher‐performance organic solar cells (OSCs) are not compatible with large‐scaled, roll‐to‐roll (R2R) manufacturing in ambient ...
Pandeng Li, Anderson Hoff, Akpeko Gasonoo, Muhammad R. Niazi, Maryam Nazari, Gregory C. Welch   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Phân lập vi khuẩn phân hủy xylene từ hệ thống xử lý nước thải

Tạp chí Khoa học Đại học Cần Thơ, 2017
Xylene là một trong những hydrocarbon thơm được sử dụng phổ biến như dung môi trong các phòng thí nghiệm. Trong công nghiệp, xylene được dùng làm dung môi để thuộc da, sản xuất đồ cao su, in ấn và là một trong các thành phần chính của xăng.
Nguyễn Thị Phi Oanh, Nguyễn Vũ Bích Triệu   +1 more
doaj   +1 more source