Extraction of Gallium(III) With a New Azo Dye in the Presence or Absence of Xylometazoline Hydrochloride [PDF]
Complex formation between Ga(III) and 6-hexyl-4-(2-thiazolylazo)resorcinol (HTAR, H2L) was studied in a water-chloroform medium, in the presence or absence of xylometazoline hydrochloride (XMH). Optimum conditions for the extraction of Ga(III) were found. In the presence of XMH, the extracted ion-associate has the formula (XMH+)[GaIIIL2], where HTAR is
Kiril Gavazov +2 more
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Comprehensive Evaluation of Xylometazoline Hydrochloride Formulations: Ex-Vivo and In-Vitro Studies
Xylometazoline is a well-established nasal decongestant that has been used alone and in combination with dexpanthenol as an over the counter (OTC) medicine. Considering the possibility of further improvement of xylometazoline nasal formulations, hyaluronic acid (HA) was evaluated as an additional ingredient. The aim of this study was to investigate the
Özgen Özer +2 more
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Using the Zero-Order Derivative Spectrum for the Quantitative Estimation of Xylometazoline Hydrochloride in Its Pure Form and Some of Its Pharmaceutical Preparations [PDF]
A new spectrophotometric method has been developed for the rapid, accurate and inexpensive determination of xylometazoline (XMH) in its pure form and in some pharmaceutical preparations, using the first derivative technique. It was found that this technique enables us to quantitatively estimate xylometazoline in a range of concentrations (5-50 µg.ml-1),
Wasan Jafar Sadiq, Imad Tarek Hanoon
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Emulsion Formulations of Indomethacine and Xylometazoline Hydrochloride for Intranasal Delivery
Nasal administration has many advantages over nasal, parenteral or oral administration. Some drugs are ineffective when administered orally due to absorption and first pass metabolism. Therefore, if the aqueous solubility problem can be overcome, the intranasal route will be an alternative method for administration.
Hatice Yeşim Karasulu +2 more
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Structure of Xylometazoline (Otrivin) Hydrochloride, an α-Adrenergic Agonist
Acta Crystallographica Section C: Crystal Structure Communications, 1986tert-Butyl-2,6-dimethylbenzyl)-4,5- dihydro-lH-imidazole hydrochloride, C 16H25N~-.Cl-, Mr=280.84, monoclinic, P21/c, a= 14.430(4), b =9.545(3), c= 12.250(4)A, fl= 104.73(2) ° , V= 1631.8A 3, Z=4, Dm=1.15, Dx=l.14gcm -3, 2(Cu Ka) = 1.5418 A, ~ = 19.72 cm -1, F(000) = 608, T= 277 (1)K, R =0.053 for 1320 observed reflec- tions. The substituted phenyl and
J K Dattagupta
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Yechiel Golander, Wayne J. DeWitte
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Extraction-Chromogenic Systems for Gallium(III) Based on Azo Dyes and Xylometazoline Hydrochloride
Russian Journal of General Chemistry, 2020Two liquid-liquid extraction-chromogenic systems for GaIII based on azo dyes (ADs) and xylometazoline hydrochloride (XMH) have been studied. The ADs used were 4-(2-pyridylazo)resorcinol (PAR) and 4-(2-thiazolylazo)resorcinol (TAR). The optimum conditions (pH, AD concentration, XMH concentration, and extraction time) for the formation of ternary ...
Danail Hristov +2 more
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A Comparison of a Synthetic Prostaglandin and Xylometazolin Hydrochloride as Nasal Decongestants
Otolaryngology–Head and Neck Surgery, 1982A synthetic prostaglandin E2 analog was compared in the dog to xylometazoline hydrochloride and natural PGE1 and PGE2 for nasal decongestant activity. Using both in vivo nasal patency tests and in vitro nasal blood vessel contraction tests, the synthetic analog was more effective, was very long‐acting, and did not change blood pressure at effective ...
R T, Jackson, J E, Birnbaum
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Objective:This study evaluated the efficacy of 0.1% xylometazoline-hydrochloride nasal decongestant spray compared to 0.9% saline nasal spray in relieving post-septoplasty clinical nasal findings and symptoms. Methods: This triple-blinded randomized-clinical-trial was conducted in 2 tertiary-care hospitals in Karachi-Pakistan.
Muhammad Hamza Dawood +2 more
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Chromium(III) forms a 1 : 3 orange-red anionic complex with 4-(2-pyridylazo)resorcinol (PAR) when heated in an acetate buffer medium (pH 4.0–5.5) on a water-bath, and this complex can be extracted quantitatively with the xylometazolonium (XMH) cation into chloroform.
Y. Anjaneyulu +2 more
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