Results 21 to 30 of about 56,320 (135)

Off‐Label, but on‐Evidence? A Review of the Level of Evidence for Pediatric Pharmacotherapy

Clinical Pharmacology &Therapeutics, Volume 112, Issue 6, Page 1243-1253, December 2022., 2022
Many drugs are still prescribed off‐label to the pediatric population. Although off‐label drug use not supported by high level of evidence is potentially harmful, a comprehensive overview of the quality of the evidence pertaining off‐label drug use in children is lacking.
Tjitske M. van der Zanden, Nori J.L. Smeets, Marika de Hoop‐Sommen, Michiel F.T. Schwerzel, Hui Jun Huang, Lieke J.C. Barten, Joyce E.M. van der Heijden, Jolien J.M. Freriksen, Akira A.L. Horstink, Inge H.G. Holsappel, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +12 more
wiley   +1 more source

The Nasal Obstruction Balance Index: A Novel Approach to Improving Correlation Between Unilateral Nasal Airway Measurements and Evaluating Nasal Airway Asymmetry

The Laryngoscope, Volume 131, Issue 12, Page E2833-E2840, December 2021., 2021
Objectives/Hypothesis Demonstrate that the Nasal Obstruction Balance Index (NOBI) model fulfils the unmet need of improving unilateral correlation between subjective and objective nasal obstruction outcome measures and identifying the more obstructed side.
Anika Kaura, Alfonso Luca Pendolino, Annakan Navaratnam, Peter J. Andrews, Terence S. Leung   +4 more
wiley   +1 more source

Effects on nasal nitric oxide production of 2 mechanisms of vasoconstriction [PDF]

, 2020
Background: Vasoconstrictor drugs reduce nitric oxide (NO) production in vitro by inhibiting the enzyme involved in the regulation of inducible and constitutive NO synthases (iNOS and cNOS).
Picado Vallés, César, Mullol i Miret, Joaquim, Valero, Antonio, Bartra Tomàs, Joan, Torrego, T., Serrano, C.   +5 more
core   +5 more sources

Rescue Therapy With Quad Zygoma After Failure of Full-Arch Implant Rehabilitation: A Retrospective Study With a Mean Follow-Up of 8 Years. [PDF]

Clin Oral Implants Res
ABSTRACT Objectives To evaluate the long‐term clinical outcomes of quad zygomatic implants (ZIs) as a rescue therapy for patients with failed full‐arch implant rehabilitation in the maxilla due to advanced peri‐implantitis. Material and Methods This was a retrospective cohort study of all patients treated with the Quad Zygoma Protocol. Primary outcomes
Fan S, Zhou W, Al-Nawas B, Valmaseda-Castellón E, Davó R.   +4 more
europepmc   +2 more sources

Formulation and Evaluation Xylometazoline Hydrochloride Mucoadhesive Nasal in Situ Gel

, 2022
The objective of research is to develop a mucoadhesive in-situ nasal gel formulation of xylometazoline hydrochloride for the treatment of allergic rhinitis to avoid possible side effects. Mucoadhesive in-situ nasal gel of xylometazoline hydrochloride was formulated by ionic gelation method using xanthan gum as ionsensitive agent and different grades of
Divya Jadhav, Misbah Shaikh, Hitesh Jain, Asit Sahu, D. B. Meshram   +4 more
openaire   +2 more sources

Application of α-adrenomimetic decongestants as chemical agents for gingival retraction [PDF]

, 2015
PURPOSE: The purpose of this study is to observe, compare and evaluate the effect of two α-adrenomimetic decongestants which are clinically approved nasal and eye drops - 0,05% xylometazoline hydrochloride and 0,05% tetrahydrozoline hydrochloride, when ...
Doychinova, Maya; Medical University of Varna, Katreva, Iveta; Medical University of Varna, Simeonov, Simeon; Medical University of Varna, Tonchev, Tsvetan; Medical University of Varna, Tivchev, Ognjan; Medical University of Varna, Abadjiev, Metodi; Medical University of Varna   +5 more
core   +11 more sources

Use of xylometazoline in hospitalised infants: is it safe? A retrospective cohort study

, 2022
Objective: When infants suffer from nasal congestion, xylometazoline spray or drops can be effective to facilitate breathing and drinking. However, case reports on side effects have resulted in international warnings regarding use of xylometazoline in ...
Saskia N de Wildt, Becker, Matthijs L., Karlijn J van Stralen, Joyce E van Tol, Marlies A van Houten, Matthijs L Becker, van Houten, Marlies A., van Stralen, Karlijn J., van Tol, Joyce E., de Wildt, Saskia N., Houten, Marlies A. van, Stralen, K.J. van, Becker, M.L., Tol, J.E. van, Wildt, S.N. de   +14 more
core   +1 more source

RP-HPLC Method of the Estimation of Xylometazoline hydrochloride in Nasal Spray Solution

, 2020
Abstract A simple, specific, precise and accurate reverse phase HPLC method has been developed for the determination of nasal decongestive, Xylometazoline hydrochloride in nasal spray solution. The chromatographic separation was achieved on column C18, 150 mmx4.6 mm, 3.5 µm, using PDA detector.
Larisa Alagić-Džambić, Minela Dacić, Amila Frljak, Ehlimana Osmanović Omerdić, Mirsad Džambić   +4 more
openaire   +1 more source

Spectrophotometric determination of xylometazoline in nasal drops [PDF]

, 2018
Objective. Spectrophotometry is one of the most widely used methods in the pharmaceutical analysis, both for the identification and for the assay of drugs. The main advantages of the method are the relative simplicity of the experiment, high sensitivity,
А. О. Donchenko, S. O. Vasyuk, N. O. Nagorna   +2 more
core   +1 more source

Development of ann calibration model for estimating xylometazoline hydrochloride concentration in crystallization process [PDF]

, 2022
In this work, the development of the ANN-based calibration models using in-situ ATR-FTIR spectroscopy for estimating the xylometazoline hydrochloride concentration in the cooling crystallization process is presented.
Gavran, Matea, Herceg, Srečko, Budimir Sacher, Josip, Bolf, Nenad, Ujević Andrijić, Željka   +4 more
openaire   +1 more source