Results 161 to 170 of about 14,835,730 (310)

El castigo de la miseria

open access: yes, 1884
Copia digital. España : Ministerio de Cultura y Deporte.
Zayas y Sotomayor, María de, 1590-ca. 1661
core  

Treatment of Malignant Tracheobronchial Stenosis with Y-Shaped Stent: A Multicenter Retrospective Study. [PDF]

open access: yesJ Clin Med
Mongiello D   +12 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Effect of a double Y-shaped miniplate over traditional miniplate in treating mandibular anterior fractures. [PDF]

open access: yesBioinformation
Satpathy S   +6 more
europepmc   +1 more source

Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors. [PDF]

open access: yesJ Med Chem, 2023
Lu W   +20 more
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

[Citando para un natural, puente y catedral de Salamanca] [Material gráfico]

open access: yes, 1905
Copia digital. Valladolid : Junta de Castilla y León.
Onetti, José
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Fortalecimiento del consejo nacional de ciencia y tecnología.

open access: yes, 2013
Breve reseña história del Consejo Nacional de Ciencia Tecnología y fortalecimientos que ha tenido desde sus inicio en 1992 hasta la ...
Consejo Nacional de Ciencia y Tecnología (CONACYT)
core  

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