Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Treatment of Malignant Tracheobronchial Stenosis with Y-Shaped Stent: A Multicenter Retrospective Study. [PDF]
Mongiello D +12 more
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Diseño de un parque científico y tecnológico de ciencias exactas e ingenierías.
Los Parques Tecnológicos son un espacio de convergencia para desarrollar I+D en el marco de una relación eficiente y pertinente de universidades y empresas; existen múltiples experiencias en Estados Unidos, Europa y Sur América de parques tecnológicos ...
Consejo Nacional de Ciencia y Tecnología (CONACYT)
core
Effect of a double Y-shaped miniplate over traditional miniplate in treating mandibular anterior fractures. [PDF]
Satpathy S +6 more
europepmc +1 more source
Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors. [PDF]
Lu W +20 more
europepmc +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Novel Use of the Raulerson Syringe and Y-Shaped Introducer Needle for Femoral Artery Cannulation. [PDF]
Kaushal A +3 more
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Novel one-step deployment of Y-shaped metal stent: no more stent-in-stent or side-by-side. [PDF]
Nagai K +6 more
europepmc +1 more source

