Results 71 to 80 of about 3,589,800 (295)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Speech enhancement using deep learning [PDF]
, 2017 This thesis explores the possibility to achieve enhancement on noisy speech signals using Deep Neural Networks. Signal enhancement is a classic problem in speech processing.
Badescu, Dan Mihai
core
Secret message capacity of a line network
, 2014 We investigate the problem of information theoretically secure communication in a line network with erasure channels and state feedback. We consider a spectrum of cases for the private randomness that intermediate nodes can generate, ranging from having ...
Czap, Laszlo +2 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Gaceta Sanitaria, 2010 Objetivos: Describir la concentración de trihalometanos (THM) y ácidos haloacéticos (AHA) del agua de consumo, valorar su variación espacio-temporal y estimar las ingestas individuales en el embarazo.
Loreto Santa Marina +8 more
doaj
Revista Enfermagem UERJ, 2019 Objective: to know the social support network used by the family to care for children with cerebral palsy. Method: this qualitative and descriptive research was conducted with twelve mothers of children with cerebral palsy assisted at a pediatric unit of
Giovana Calcagno Gomes +5 more
doaj +1 more source
TPU Cloud-Based Generalized U-Net for Eye Fundus Image Segmentation [PDF]
, 2019 Medical images from different clinics are acquired with different instruments and settings. To perform segmentation on these images as a cloud-based service we need to train with multiple datasets to increase the segmentation independency from the ...
Civit Balcells, Antón +4 more
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Distinct cerebral pathways for object identity and number in human infants. [PDF]
PLoS Biology, 2008 All humans, regardless of their culture and education, possess an intuitive understanding of number. Behavioural evidence suggests that numerical competence may be present early on in infancy. Here, we present brain-imaging evidence for distinct cerebral
Véronique Izard +2 more
doaj +1 more source