Results 111 to 120 of about 10,446,015 (290)

X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells

Biology of Sex Differences, 2018
Background Sexual dimorphism in DNA methylation levels is a recurrent epigenetic feature in different human cell types and has been implicated in predisposition to disease, such as psychiatric and autoimmune disorders. To elucidate the genetic origins of
Bianca Ho, Keelin Greenlaw, Abeer Al Tuwaijri, Sanny Moussette, Francisco Martínez, Elisa Giorgio, Alfredo Brusco, Giovanni Battista Ferrero, Natália D. Linhares, Eugênia R. Valadares, Marta Svartman, Vera M. Kalscheuer, Germán Rodríguez Criado, Catherine Laprise, Celia M. T. Greenwood, Anna K. Naumova   +15 more
doaj   +1 more source

The Neolithic transition in Europe: archaeological models and genetic evidence [PDF]

, 2003
The major pattern in the European gene pool is a southeast-northwest frequency gradient of classic genetic markers such as blood groups, which population geneticists initially attributed to the demographic impact of Neolithic farmers dispersing from the ...
Richards, Martin B.
core   +4 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

#1085 Y-chromosome detection and oncogenic risks in turner syndrome [PDF]

, 2023
Balkiss Abdelmoula, N. Bouayed Abdelmoula   +1 more
openalex   +1 more source

The complete sequence of a human Y chromosome

bioRxiv, 2023
A. Rhie, S. Nurk, Monika Cechova, Savannah J. Hoyt, Dylan J. Taylor, Nicolas Altemose, P. Hook, S. Koren, M. Rautiainen, I. Alexandrov, J. Allen, Mobin Asri, Andrey V. Bzikadze, Nae-Chyun Chen, Chen-Shan Chin, M. Diekhans, Paul Flicek, G. Formenti, Arkarachai Fungtammasan, C. G. Girón, Erik K. Garrison, Ariel Gershman, J. Gerton, Patrick G. S. Grady, A. Guarracino, Leanne Haggerty, R. Halabian, Nancy F. Hansen, Robert S. Harris, Gabrielle Hartley, William T. Harvey, Marina Haukness, Jakob M. Heinz, Thibaut Hourlier, R. Hubley, S. Hunt, Stephen Hwang, Miten Jain, Rupesh K. Kesharwani, Alexandra P. Lewis, Heng Li, Glennis A. Logsdon, Julian K. Lucas, W. Makałowski, C. Markovic, Fergal J. Martin, Ann M. Mc Cartney, R. McCoy, Jennifer McDaniel, B. McNulty, P. Medvedev, Alla Mikheenko, Katherine M. Munson, T. Murphy, Hugh E. Olsen, Nathan D. Olson, L. F. Paulin, David Porubsky, T. Potapova, F. Ryabov, S. Salzberg, M. Sauria, F. Sedlazeck, Kishwar Shafin, V. Shepelev, Alaina Shumate, Jessica M. Storer, Likhitha Surapaneni, A. M. Taravella Oill, F. Thibaud-Nissen, W. Timp, Marta Tomaszkiewicz, Mitchell R. Vollger, B. Walenz, Allison C. Watwood, Matthias H. Weissensteiner, A. Wenger, M. Wilson, Samantha Zarate, Yiming Zhu, J. Zook, E. Eichler, R. O’Neill, M. Schatz, K. Miga, K. Makova, A. Phillippy   +86 more
semanticscholar   +1 more source

Analysis of the Mouse Y Chromosome by Single-Molecule Sequencing With Y Chromosome Enrichment

Frontiers in Genetics, 2020
Since human and mouse Y chromosomes contain repeated sequences, it is difficult to determine the precise sequences and analyze the function of individual Y chromosome genes. Therefore, the causes of many diseases and abnormalities related to Y chromosome
Yuki Yano, Tomoki Chiba, Hiroshi Asahara, Hiroshi Asahara   +3 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Y chromosome loss in cancer drives growth by evasion of adaptive immunity

Nature, 2023
Hany A. Abdel-Hafiz, J. Schafer, Xingyu Chen, Tong Xiao, Timothy D. Gauntner, Zihai Li, D. Theodorescu   +6 more
semanticscholar   +1 more source

Ethnic identification of the Kazakhs by subclads of the Y-chromosome haplogroup C2

Nomadic Civilization: Historical Research
Y-chromosome haplogroups (transmitted through the male line) C2, O and D are called Mongolian. Among the Kazakhs of Kazakhstan, 40–52 % are carriers of haplogroup C2, 8 % are carriers of O and up to 1 % are carriers of D.
A. M. Tyurin
doaj   +1 more source

Cytotaxonomy of two species of genus Chrysolaena H. Robinson, 1988 (Vernonieae, Asteraceae) from Northeast Paraguay [PDF]

, 2014
Chromosome counts and karyotypes of two species of Chrysolaena H. Robinson 1988 are presented in this paper. Mitotic analysis revealed that both taxa have x=10, a basic chromosome number considered characteristic of the genus.
Dematteis, Massimiliano, Via Do Pico, Gisela Mariel   +1 more
core   +5 more sources