Results 151 to 160 of about 10,446,015 (290)

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Selection and separation of X‐ and Y‐ chromosome‐bearing mammalian sperm [PDF]

, 1988
Barton L. Gledhill
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Gene Duplication, Gene Conversion and the Evolution of the Y Chromosome [PDF]

, 2010
Tim Connallon, Andrew G. Clark
openalex   +1 more source

Comparison of genetic and linguistic data as an approach to studying human migrations

Учёные записки Казанского университета: Серия Естественные науки, 2018
The origin of humans and their settling around the globe are explored using various scientific methods. Genomic profiling data increasing in volume every day are of particular interest to researchers of these problems.
E.A. Boulygina, V.V. Bochkarev, V.D. Solovyev   +2 more
doaj  

Forensic Genetics: A Machine Learning Algorithm for Mutation Modelling

RevSALUS
Microsatellites or short tandem repeats (STRs) are the most used markers in population and forensic genetics due to their high polymorphism that is consequence of high germinal mutation rates.
Sofia Antão Sousa, Leonor Gusmão, Marisa Faustino, António Amorim, Nádia Pinto   +4 more
doaj   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

A study of a Chromosome-level Genome Assembly and the Origin of Neo-Y Chromosome to the X1X2Y System in the Male Barred knifejaw Oplegnathus fasciatus. Xiao et al.

, 2020
Yongshuang Xiao
openalex   +1 more source

High Y-chromosomal diversity and low relatedness between paternal lineages on a communal scale in the Western European Low Countries during the surname establishment [PDF]

, 2015
Maarten Larmuseau, Nele Boon, Nancy Vanderheyden, Anneleen Van Geystelen, Hendrik Larmuseau, Koenraad Matthys, Wim De Clercq, Ronny Decorte   +7 more
openalex   +1 more source

Turkish Cypriot paternal lineages bear an autochthonous character and closest resemblance to those from neighbouring Near Eastern populations

Annals of Human Biology, 2017
Background: Cyprus is an island in the Eastern Mediterranean Sea with a documented history of human settlements dating back over 10,000 years. Aim: To investigate the paternal lineages of a representative population from Cyprus in the context of the ...
Cemal Gurkan, Huseyin Sevay, Damla Kanliada Demirdov, Sinem Hossoz, Deren Ceker, Kerem Teralı, Ayla Sevim Erol   +6 more
doaj   +1 more source