Results 261 to 270 of about 10,446,015 (290)

The phylogenetic and geographic structure of Y-chromosome haplogroup R1a

European Journal of Human Genetics, 2014
P. Underhill, G. D. Poznik, S. Rootsi, M. Järve, A. A. Lin, Jianbin Wang, Ben Passarelli, Jad N Kanbar, Natalie M. Myres, Roy J. King, Julie Di Cristofaro, Hovhannes Sahakyan, D. Behar, A. Kushniarevich, J. Šarac, Tena Šarić, P. Rudan, A. K. Pathak, G. Chaubey, V. Grugni, O. Semino, L. Yepiskoposyan, A. Bahmanimehr, S. Farjadian, O. Balanovsky, E. Khusnutdinova, R. J. Herrera, J. Chiaroni, C. Bustamante, S. Quake, T. Kivisild, R. Villems   +31 more
semanticscholar   +1 more source

Pathogenicity of Mediator Complex Subunit 27 (MED27) in a Neurodevelopmental Disorder with Cerebellar Atrophy

Advanced Science, EarlyView.
MED27 is one of the 26 subunits in the human Mediator complex (MED). Neurodevelopmental disorder‐causing MED27 genetic variants induce instability of MED, leading to disrupted DNA occupancy, altered chromatin interaction, and subsequent transcriptional dysregulation of critical downstream genes, including master regulatory transcription factors ...
Nuermila Yiliyaer, Xiaocheng Li, Tianyu Guo, Haiying Zhou, Lihai Gong, Luowei Yuan, Yang Fu, Yulong Qiao, Ying Lam Lui, Nuo Chen, Pengfei Lin, Hoi Hung Cheung, Ho Ko, Linyan Meng, Xiao Chen, Yong Lei, Kin Ming Kwan, Huating Wang, Shen Gu   +18 more
wiley   +1 more source

Human Y chromosome azoospermia factors (AZF) mapped to different subregions in Yq11.

Human Molecular Genetics, 1996
P. Vog, A. Edelmann, S. Kirsch, O. Henegariu, P. Hirschmann, F. Kiesewetter, F. Köhn, W. Schill, S. Farah, C. Ramos, M. Hartmann, W. Hartschuh, D. Meschede, H. Behre, A. Castel, E. Nieschlag, W. Weidner, H. Gröne, A. Jung, W. Engel, G. Haidl   +20 more
semanticscholar   +1 more source

Plant Virus‐Induced Inheritable Apoptosis Drives Reproductive Costs in Female Insect Vectors to Balance Viral Biparental Transmission

Advanced Science, EarlyView.
Rice gall dwarf virus (RGDV), transmitted biparentally by leafhopper vector to their offspring, exploits the capsid protein to induce inheritable ovarian apoptosis via insulin‐driven PI3K/AKT/FoxO signaling axis. This mechanism enhances infection but reduces female reproductive fitness, causing inefficient maternal transmission.
Haibo Wu, Wenqiang Wan, Qingquan Liang, Hengsong Yang, Chengcong Lu, Taiyun Wei, Qian Chen   +6 more
wiley   +1 more source

Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA–binding protein gene

Nature Genetics, 1995
R. Reijo, Tien-Yi Lee, P. Salo, R. Alagappan, L. Brown, Michael Rosenberg, S. Rozen, T. Jaffe, D. Straus, O. Hovatta, A. Chapelle, S. Silber, D. Page   +12 more
semanticscholar   +1 more source

Super‐Resolution Compatible DNA Labeling Technique Reveals Chromatin Mobility and Organization Changes During Differentiation

Advanced Science, EarlyView.
A novel chromatin‐labeling probe is developed to investigate chromatin mobility during differentiation. The silicon rhodamine–conjugated dCTP is efficiently delivered into iPSCs and NSCs using a synthetic transporter. Super‐resolution microscopy and single‐particle tracking show decreased chromatin mobility during differentiation.
Maruthi K. Pabba, Miroslav Kuba, Tomáš Kraus, Kerem Celikay, Janis Meyer, Sunil Kumar Pradhan, Andreas Maiser, Hartmann Harz, Heinrich Leonhardt, Karl Rohr, Michal Hocek, M. Cristina Cardoso   +11 more
wiley   +1 more source

Two Y Genes Can Replace the Entire Y Chromosome for Assisted Reproduction in the Mouse

Science, 2014
Y. Yamauchi, Jonathan M. Riel, Z. Stoytcheva, M. Ward   +3 more
semanticscholar   +1 more source

Molecular Chain Elongation Mechanism for n‐Caproate Biosynthesis by Megasphaera Hexanoica

Advanced Science, EarlyView.
The medium‐chain carboxylate‐producing microbe Megasphaera hexanoica is analyzed through genomics, transcriptomics, and metabolic engineering. The n‐caproate biosynthetic pathway is reconstructed in Escherichia coli, highlighting MhTHL as a key β‐ketothiolase. Structural analysis and mutagenesis reveal that MhTHL has a distinct substrate‐binding pocket,
Byoung Seung Jeon, Eun‐Jung Kim, Hogyun Seo, Hyunjin Kim, Seungjin Shin, Caroline Schlaiß, Largus T. Angenent, Kyung‐Jin Kim, Byoung‐In Sang   +8 more
wiley   +1 more source

THE STORY OF TWO NORTHWARD MIGRATIONSORIGINS OF FINNO-PERMIC AND BALTO-SLAVIC LANGUAGES IN NORTHEAST EUROPE, BASED ON HUMAN Y-CHROMOSOME HAPLOGROUPS337

, 2014
Csaba Horváth
openalex   +1 more source

Estimating Tempo and Mode of Y Chromosome Turnover: Explaining Y Chromosome Loss With the Fragile Y Hypothesis

Genetics, 2014
Heath Blackmon, Jeffery P. Demuth
semanticscholar   +1 more source