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Nature, 2014
Comparisons of Y-chromosome sequences in various mammals reveal abundant gene loss early in the chromosome's evolution but remarkable gene stability across the Y chromosomes of extant species.
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Comparisons of Y-chromosome sequences in various mammals reveal abundant gene loss early in the chromosome's evolution but remarkable gene stability across the Y chromosomes of extant species.
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Chromosome Y et infertilité masculine : qu'est-ce qu'un chromosome Y normal ?
Journal de la Société de Biologie, 2008The human Y chromosome contains a number of genes and gene families that are essential for germ cell development and maintenance. Many of these genes are located in highly repetitive elements that are subject to rearrangements. Deletion of azoospermia factor (AZF) regions AZFa, AZFb, and AZFc are found in approximately 10-15% of men with severe forms ...
Jacqueline Mandelbaum +6 more
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2020
Genetic abnormalities may be associated with problems in the production and transport of sperm and may be present in the form of chromosomal, genetic, nucleotide, or epigenetic modifications and may represent one of the most clinically important aspects of male factor infertility.
Igor Faria Dutra, Matheus Roque
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Genetic abnormalities may be associated with problems in the production and transport of sperm and may be present in the form of chromosomal, genetic, nucleotide, or epigenetic modifications and may represent one of the most clinically important aspects of male factor infertility.
Igor Faria Dutra, Matheus Roque
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Science, 2016
Sex Chromosome The mammalian Y chromosome encodes a specialized set of genes that are essential for male viability and fertility. In particular, the sex-determining region Y (SRY) protein is necessary to initiate male sex determination. However, Yamauchi et al. show that the functions of the entire Y chromosome can be replaced with only two genes.
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Sex Chromosome The mammalian Y chromosome encodes a specialized set of genes that are essential for male viability and fertility. In particular, the sex-determining region Y (SRY) protein is necessary to initiate male sex determination. However, Yamauchi et al. show that the functions of the entire Y chromosome can be replaced with only two genes.
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Human Y-chromosome variation in the genome-sequencing era
Nature reviews genetics, 2017M. Jobling, C. Tyler-Smith
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