Results 21 to 30 of about 10,690,340 (404)

Molecular Dissection Using Array Comparative Genomic Hybridization and Clinical Evaluation of An Infertile Male Carrier of An Unbalanced Y;21 Translocation: A Case Report and Review of The Literature [PDF]

International Journal of Fertility and Sterility, 2016
Chromosomal defects are relatively frequent in infertile men however, translocations between the Y chromosome and autosomes are rare and less than 40 cases of Y-autosome translocation have been reported.
Alfredo Orrico, Giuseppina Marseglia, Chiara Pescucci, Ambra Cortesi, Paola Piomboni, Andrea Giansanti, Francesca Gerundino, Roberto Ponchietti   +7 more
doaj   +1 more source

Quantitative analysis of Y-Chromosome gene expression across 36 human tissues

Genome Research, 2020
Little is known about how human Y-Chromosome gene expression directly contributes to differences between XX (female) and XY (male) individuals in nonreproductive tissues.
Alexander K. Godfrey, S. Naqvi, Lukas Chmatal, Joel M. Chick, R. Mitchell, S. Gygi, H. Skaletsky, D. Page   +7 more
semanticscholar   +1 more source

The outcomes of fetal cell microchimerism in the mother

Biomedical Research Journal, 2021
The presence of small quantities of genetically heterogeneous cells in an organism is known as microchimerism. Fetal microchimerism is the presence of small quantities of fetal cells in the maternal system during and after pregnancy.
Anushka Nikhil Alekar
doaj   +1 more source

The degeneration of Y chromosomes [PDF]

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2000
Y chromosomes are genetically degenerate, having lost most of the active genes that were present in their ancestors. The causes of this degeneration have attracted much attention from evolutionary theorists. Four major theories are reviewed here: Muller's ratchet, background selection, the Hill–Robertson effect with weak selection, and the ‘hitchhiking’
Brian Charlesworth, Deborah Charlesworth
openaire   +3 more sources

The Dutch Y-chromosomal landscape [PDF]

European Journal of Human Genetics, 2019
AbstractPrevious studies indicated existing, albeit limited, genetic-geographic population substructure in the Dutch population based on genome-wide data and a lack of this for mitochondrial SNP based data. Despite the aforementioned studies, Y-chromosomal SNP data from the Netherlands remain scarce and do not cover the territory of the Netherlands ...
Kristiaan J. van der Gaag, Kristiaan J. van der Gaag, Manfred Kayser, Eveline Altena, Thirsa Kraaijenbrink, Oscar Lao, Oscar Lao, Maarten Larmuseau, Ronny Decorte, Peter de Knijff, Risha Smeding   +10 more
openaire   +5 more sources

Assessment of Correlation between Androgen Receptor CAG Repeat Length and Infertility in Infertile Men Living in Khuzestan, Iran [PDF]

International Journal of Fertility and Sterility, 2015
Background The androgen receptor (AR) gene contains a polymorphic trinucleotide repeat that encodes a polyglutamine tract in its N-terminal transactivation domain (N- TAD).
Saeid Reza Khatami, Hamid Galehdari, Abdorrahman Rasekh, Hayat Mombeini, Elham Konar   +4 more
doaj   +1 more source

Effective Model of Loop Extrusion Predicts Chromosomal Domains [PDF]

Phys. Rev. E 102, 032414 (2020), 2020
An active loop-extrusion mechanism is regarded as the main out--of--equilibrium mechanism responsible for the structuring of megabase-sized domains in chromosomes. We developed a model to study the dynamics of the chromosome fibre by solving the kinetic equations associated with the motion of the extruder.
arxiv   +1 more source

A family case of fertile human 45,X,psu dic(15;Y) males [PDF]

, 2006
We report on a familial case including four male probands from three generations with a 45,X,psu dic(15;Y)(p11.2;q12) karyotype. 45,X is usually associated with a female phenotype and only rarely with maleness, due to translocation of small Y chromosomal
Andersson M, Baumstark A, Buonadonna AL, C.S. Nagarajappa, Callen DF, Charchar FJ, Fracarro M, Freije D, Gal A, Haaf T, Hsu TC, I. Hansmann, I. Palaniappan, Koiffmann CP, Ma NS, Maserati E, Matthey R, N. Chandra, P.M. Gopinath, R. Wimmer, Ried T, Schempp W, Schiebel K, Schmid M, Siffroi JP, Subrt I, Tiemeier DC, W. Schempp, Weber B, White LM   +29 more
core   +1 more source

The Origin of a New Sex Chromosome by Introgression between Two Stickleback Fishes. [PDF]

, 2019
Introgression is increasingly recognized as a source of genetic diversity that fuels adaptation. Its role in the evolution of sex chromosomes, however, is not well known. Here, we confirm the hypothesis that the Y chromosome in the ninespine stickleback,
Abbott, Alexander, Anders, Bachtrog, Bachtrog, Bachtrog, Bronson, Browning, Carling, Carneiro, Charlesworth, Charlesworth, Choi, Cook, Corcoran, Coyne, Coyne, Danecek, DePristo, Edwards, Glazer, Green, Groves Dixon, Hagen, Irwin, Ishikawa, JanouŠek, Jay, Jombart, Jombart, Jun Kitano, Krueger, Langmead, Li, Li, Lindholm, Love, Luo, Mark Kirkpatrick, Martin, Martin, Martin, Meguro, Melissa Wilson Sayres, Muirhead, Natri, Neafsey, Nei, O’Neill, Payseur, Petit, Presgraves, Quinlan, Ravinet, Ross, Saetre, Sankararaman, Schwander, Sciuchetti, Smit, Stamatakis, Storchová, Stölting, Sun, Takahashi, Takahashi, Toews, Tosi, Toups, Tuttle, van Doorn, Vicoso, von Hippel, Wang, White, Yang, Yoshida, Yoshida, Úbeda   +78 more
core   +1 more source

Y-chromosome evolution: emerging insights into processes of Y-chromosome degeneration [PDF]

Nature Reviews Genetics, 2013
The human Y chromosome is intriguing not only because it harbours the master-switch gene that determines gender but also because of its unusual evolutionary history. The Y chromosome evolved from an autosome, and its evolution has been characterized by massive gene decay.
D. Bachtrog
semanticscholar   +3 more sources