Protective Gene Expression Changes Elicited by an Inherited Defect in Photoreceptor Structure [PDF]
, 2012 Inherited defects in retinal photoreceptor structure impair visual transduction, disrupt relationship with the retinal pigment epithelium (RPE), and compromise cell viability.
A Bessis +69 more
core +4 more sources
Challenges in constructing genetic instruments for pharmacologic therapies [PDF]
arXiv, 2020 The genes that encode the targets of most therapies do not have rare variants with large-effect or common variants with moderate effects on the biomarker reflecting the pharmacologic action of the corresponding therapy. Therefore, providing genetic target validation for most therapies is challenging.
arxiv
Exploring biomedical and traditional care pathways for people with psychosis in Karachi, Pakistan [PDF]
, 2023 BACKGROUND: Psychosis is known to have an adverse impact on an individual’s quality of life, social and occupational functioning. A lack of treatment options for psychotic disorders such as schizophrenia contributes to adverse outcomes for individuals. A
Fearon, Pasco +6 more
core
Therapy Control and Patient Safety for Proton Therapy [PDF]
CERN Yellow Report CERN-2017-004-SP pp. 309-319, 2018 This contribution describes general concepts for control and safety systems in proton therapy. These concepts are illustrated by concrete examples implemented in the Proscan facility at PSI.
arxiv +1 more source
Indigenous knowledge and its implication for agricultural development and agricultural education: a case study of the Vedic tradition in Nepal [PDF]
, 1993 This dissertation is about the meaning and relevance, in today\u27s world, of indigenous knowledge, and particularly the traditional cosmologies and sacred beliefs that underly this knowledge. The case of Vedic knowledge in Nepal is studied to illustrate
Willett, Anthony B. J.
core +2 more sources
Deterministic and Stochastic in-host Tuberculosis Models for Bacterium-directed and Host-directed Therapy Combination [PDF]
arXiv, 2021 Mycobacterium tuberculosis infection can involve all immune system components and can result in different disease outcomes. The antibiotic TB drugs require strict adherence to prevent both disease relapse and mutation of drug- and multidrug-resistant strains.
arxiv
Rasayana: Preventive measures for Non-Communicable Diseases (NCDs) [PDF]
The most valuable possession we may have ourselves is good health. Everyone aspires to live a healthy life. One of the obstacles to achieving them is non-communicable diseases.
Madugula Sruthi, Maindoli, Geeta
core +2 more sources
KSoF: The Kassel State of Fluency Dataset -- A Therapy Centered Dataset of Stuttering [PDF]
arXiv, 2022 Stuttering is a complex speech disorder that negatively affects an individual's ability to communicate effectively. Persons who stutter (PWS) often suffer considerably under the condition and seek help through therapy. Fluency shaping is a therapy approach where PWSs learn to modify their speech to help them to overcome their stutter.
arxiv
Literacy practices of Nepalese children in the UK: A linguistic ethnographic study [PDF]
, 2022 This linguistic ethnographic study explores the literacy practices of Nepalese children in the UK. Nine children (age 8-13) were observed over the course of one academic year, in their Nepalese complementary school (NCS).
Knee, Sarah Katherine
core
An integrative approach towards prevention & management of psychological illnesses during COVID 19 crisis [PDF]
, 2020 Widespread outbreaks of infectious disease, such as COVID-19, are associated with psychological distress and symptoms of mental illness. To date (June 29th, 2020), over 10,021,401 confirmed cases and 499,913 deaths attributable to this disease have been ...
Dr. Deepti Sharma +3 more
core +2 more sources