Results 51 to 60 of about 1,306,427 (298)

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Epidemiological Studies on Fetal Loss – Better Data and Research Methods are Needed

Clinical Epidemiology, 2020
Jørn Olsen,1 Zeyan Liew2 1Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus N 8200, Denmark; 2Department of Environmental Health Sciences, Yale School of Public Health, Yale Center for Perinatal, Pediatric, and Environmental ...
Olsen J, Liew Z
doaj  

Religious Dimensions of Democratization Processes in Muslim-Majority Nations

American Journal of Islam and Society, 2013
The 41st AMSS annual conference, held on 29 September 2012 at Yale Divinity School, brought together scholars and activists to address “Religious Dimensions of Democratization Processes in Muslim-Majority Nations.” The event, consisting of four panels ...
Celene Ayat Lizzio
doaj   +1 more source

The Original Beat: An Electronic Music Production System and Its Design [PDF]

, 2019
The barrier to entry in electronic music production is high. It requires expensive, complicated software, extensive knowledge of music theory and experience with sound generation.
Kordonsky, Matt, Quintero, Christian, Yale, Eli   +2 more
core   +1 more source

Coupled Above‐ and Belowground Ecosystem Stability Worldwide

Advanced Science, EarlyView.
Are the worlds above and below our feet in sync? This global exploration reveals an entangled fate between above‐ and belowground ecosystem stability. It identifies arid regions as hotspots for this coupling and highlights temperature stability as a vital safeguard for maintaining ecosystem balance across our warming planet.
Zexin Meng, Huiwen Li, Yiping Wu, Peter B. Reich, Nico Eisenhauer, Diego Abalos, Daniel Revillini, Shuguang Liu, Wende Yan, Ji Chen, Alexey Voinov, Zhifeng Yang, Ying‐Ping Wang, Fubo Zhao, Linjing Qiu, Jingfeng Xiao, Shantao An, Guopeng Liang, Manuel Delgado‐Baquerizo   +18 more
wiley   +1 more source

The Southern Proper Motion Program IV. The SPM4 Catalog

, 2011
We present the fourth installment of the Yale/San Juan Southern Proper Motion Catalog, SPM4. The SPM4 contains absolute proper motions, celestial coordinates, and (B,V) photometry for over 103 million stars and galaxies between the south celestial pole ...
Anderson, Bedin, Carlos E. López, Casetti-Dinescu, Casetti-Dinescu, Casetti-Dinescu, Dana I. Casetti-Dinescu, Danilo Castillo, David G. Monet, David Herrera, Dinescu, Dinescu, Dinescu, Fedorov, Girard, Girard, Girard, Hanson, Høg, Kalirai, Kalirai, Kallivayalil, Katherine Vieira, Monet, Norbert Zacharias, Perryman, Platais, Platais, Roeser, Skrutskie, Terrence M. Girard, Timothy C. Beers, van Altena, van Altena, Vieira, William F. van Altena, Young Sun Lee, Zacharias, Zacharias, Zwitter   +39 more
core   +1 more source

Extension into the entrance channel of HIV-1 reverse transcriptase—Crystallography and enhanced solubility [PDF]

, 2013
Non-nucleoside inhibitors of HIV-1 reverse transcriptase (HIV-RT) are reported that feature extension into the entrance channel near Glu138. Complexes of the parent anilinylpyrimidine 1 and the morpholinoethoxy analog 2j with HIV-RT have received ...
Anderson, Karen S., Arnold, Eddy, Bauman, Joseph D., Bollini, Mariela, Cisneros, José A., Das, Kalyan, Frey, Kathleen M., Jorgensen, William L., Spasov, Krasimir A.   +8 more
core   +1 more source

Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss

Advanced Science, EarlyView.
 . ABSTRACT Sensorineural hearing loss (SNHL) induced by noise or aminoglycoside antibiotics is a significant public health concern without any FDA‐approved pharmaceutical therapies. Dysregulation of iron homeostasis and its subsequently induced ferroptosis has increasingly been identified as a key mechanism underlying cochlear hair cell (HC) damage ...
Huanyu Mao, Xiang Li, Yaqi Liao, Liman Liu, Xian Gao, Hailiang Lin, Wenli Ni, Huawei Li, Yan Chen, Wenyan Li   +9 more
wiley   +1 more source

Physical Examination Signs of Inspection and Medical Eponyms in Pericarditis Part I: 1761 to 1852

Erciyes Medical Journal, 2019
The history of pericarditis involves the recognition of signs and symptoms detected using the physical examination skills such as inspection, palpation, percussion, and auscultation. Pericarditis is the term used to describe the spectrum of diseases that
Fan Ye, Halil Tekiner, Eileen Yale, Joseph Mazza, Steven Yale   +4 more
doaj   +1 more source

The Logologist\u27s Love Letter [PDF]

, 1983
The following letter was written by Richard Lederer after a fight with his wife-to-be, Carol, when he was a student at Yale and she at Pembroke.
Lederer, Richard M.
core   +1 more source