Results 81 to 90 of about 1,306,427 (298)

Novel Monoclonal Antibody Detects Small Aβ Oligomers More Sensitively Than Lecanemab in Alzheimer's Disease CSF, Serum and Culture Media

open access: yesAnnals of Neurology, EarlyView.
Objective Aqueously diffusible oligomers of the amyloid β‐protein (oAβ) are neurotoxic and play a role in neuronal dysfunction in Alzheimer's disease (AD). Accurate quantification of oAβ in brains and biofluids could be valuable for understanding and monitoring AD.
Yi Ran Xu   +11 more
wiley   +1 more source

Hematoma Interleukin‐1 Receptor Antagonist Concentrations Predict Long‐Term Outcome in Acute Human Intracerebral Hemorrhage

open access: yesAnnals of Neurology, EarlyView.
Objectives The interleukin (IL)‐1, IL‐6, and C‐reactive protein (CRP) pathway is central to the immune response after intracerebral hemorrhage (ICH). We tested for associations between hematoma and plasma cytokine concentrations and patient outcomes in Minimally Invasive Surgery Plus Rt‐PA for ICH Evacuation Phase III (MISTIE III) participants ...
Adrian R. Parry‐Jones   +54 more
wiley   +1 more source

Regional Brain Volume and Cognitive Outcome in Preterm Infants

open access: yesPediatric Neurology Briefs, 2000
Regional cortical volumes, measured by structural magnetic resonance imaging scans, were compared in 25 eight-year-old preterm children and 39 term control children, in a study performed at Yale and Brown University Medical Schools, and reported from the
J Gordon Millichap
doaj   +1 more source

The relationship between form and function of the carnivore mandible

open access: yesThe Anatomical Record, EarlyView.
Abstract Dietary morphology diversified extensively in Carnivoraformes (living Carnivora and their stem relatives) during the Cenozoic (the last 66 million years) as they evolved to capture, handle, and process new animal and plant diets. We used 3D geometric morphometrics, mechanical advantage, and finite element analysis to test the evolutionary ...
Charles J. Salcido, P. David Polly
wiley   +1 more source

Attacking the public health crisis of hepatocellular carcinoma at its roots

open access: yesHepatology, EarlyView., 2022
Abstract As the third most common cause of cancer‐related death worldwide with significant mortality rates in the United States, hepatocellular carcinoma has strong association with cirrhosis and chronic hepatitis B virus (HBV) with a growing at‐risk population from the rise in chronic liver disease from alcohol use and nonalcoholic fatty liver disease.
Hannah M. Lee   +3 more
wiley   +1 more source

A detailed redescription of a skeletally immature ‘Redondasaurus’ suggests ontogenetic transformations in the taxon mirror phytosaurian morphological evolution

open access: yesThe Anatomical Record, EarlyView.
Abstract The study of morphological evolution is fundamentally tied to ontogeny, yet studies of these heterochronic processes in the fossil record are rare. Fossils belonging to an ontogenetic series are difficult to assign to an ontogenetic stage due to inconsistent proxies for skeletal ages, challenging to taxonomically assign due to morphological ...
Erika R. Goldsmith, Michelle R. Stocker
wiley   +1 more source

Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study

open access: yesHepatology, EarlyView., 2022
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel   +93 more
wiley   +1 more source

New craniodental materials of Falcarius utahensis (Theropoda: Therizinosauria) reveal patterns of intraspecific variation and cranial evolution in early coelurosaurians

open access: yesThe Anatomical Record, EarlyView.
Abstract Despite documented ecomorphological shifts toward an herbivorous diet in several coelurosaurian lineages, the evolutionary tempo and mode of these changes remain poorly understood, hampered by sparse cranial materials for early representatives of major clades. This is particularly true for Therizinosauria, with representative crania best known
William J. Freimuth, Lindsay E. Zanno
wiley   +1 more source

From the TAP for the Abdomen to the ESP for the Spine: Evidence-Based Medicine and the Inertia of Progress [Letter]

open access: yesJournal of Pain Research, 2023
Bartlomiej Bartkowiak, Jinlei Li Department of Anesthesiology, Yale University School of Medicine, New Haven, CT, USACorrespondence: Jinlei Li, Department of Anesthesiology, Yale University School of Medicine, PO Box 208051, New Haven, CT, 06520-8051 ...
Bartkowiak B, Li J
doaj  

The cranial, mandibular, and hyoid anatomy of softshell turtles (Trionychidae): A revised character list for phylogenetic analysis

open access: yesThe Anatomical Record, EarlyView.
Abstract Softshell turtles (Pan‐Trionychidae) are an early branching clade of hidden‐necked turtles (Cryptodira) with a rich fossil record extending back to the Early Cretaceous. The evolutionary history of softshell turtles is still unresolved because of their conservative morphology combined with high levels of polymorphism related to morphological ...
Léa C. Girard, Walter G. Joyce
wiley   +1 more source

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