Results 51 to 60 of about 85,072,915 (286)

Digoxin Alleviates Osteoarthritis by Inhibiting Macrophage Extracellular Trap Formation via Disruption of the LSP1‐SOD1 Interaction

open access: yesAdvanced Science, EarlyView.
Synovial macrophages in osteoarthritis upregulate LSP1, which directly binds and inhibits SOD1, triggering a redox imbalance that activates both NOX and mitochondrial ROS pathways. This cascade drives the release of macrophage extracellular traps (METs), causing chondrocyte damage and disease progression.
Yankai Pan   +9 more
wiley   +1 more source

Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study

open access: yesHepatology, EarlyView., 2022
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel   +93 more
wiley   +1 more source

Yale in New Haven [PDF]

open access: yes, 1962
Yale has been a part of the New Haven scene for such a long time that we are prone to forget this was not its original location. Yale moved to New Haven from Saybrook, and the circumstances under which it came here are interesting.
Yale University
core   +1 more source

Insights into the Role of Commensal-Specific T Cells in Intestinal Inflammation

open access: yesJournal of Inflammation Research, 2022
Arne Gehlhaar,1,* Ashwin Inala,1,* Dhana Llivichuzhca-Loja,1,* Tatiana N Silva,1,* Comfort Y Adegboye,2 Amy E O’Connell,2,3 Liza Konnikova1,4,5 1Department of Pediatrics, Yale University, New Haven, CT, USA; 2Division of Newborn Medicine,
Gehlhaar A   +6 more
doaj  

Hicks, Richard III: The Self-Made King (Yale University Press, 2019)

open access: yesRoyal Studies Journal, 2020
Review of Michael Hicks, Richard III: The Self-Made King (New Haven: Yale University Press, 2019).
Marina Gerzic
doaj   +1 more source

A Living Multi‐Omics PDX Biobank of High‐Risk Sarcomas Reveals ecDNA‐Driven Oncogene Amplification in Osteosarcoma and Enables Preclinical Precision Oncology

open access: yesAdvanced Science, EarlyView.
A living multi‐omics sarcoma PDX biobank is enriched for high‐risk disease and preserves key patient tumor features at histopathological and molecular levels. Integrated profiling reveals ecDNA‐driven oncogene amplification in osteosarcoma and preferential retention of ecDNA during PDX evolution.
Weisong Zhao   +34 more
wiley   +1 more source

Nota Bene: News from the Yale Library [PDF]

open access: yes, 2012
Nota Bene is published during the academic year to acquaint the Yale community and others with the resources of the Yale ...
Yale University Library
core   +4 more sources

A Transcriptionally Distinct Intermediate Activation State Precedes Langerhans Cell Migration From the Epidermis

open access: yesAdvanced Science, EarlyView.
A transcriptionally distinct intermediate Langerhans cell state is identified between steady and migratory populations during skin injury. Integrated single‐cell transcriptomics, flow cytometry, and intravital imaging reveal state‐specific markers and implicate complement signaling, particularly C3, in regulating Langerhans cell accumulation near ...
Artem Kiselev   +5 more
wiley   +1 more source

Yale School of Nursing Alumnae News 1933 [PDF]

open access: yes, 1933
Introduction reads: this is an attempt at an informal, newsy bulletin for the alumnae of the Yale University School of Nursing, 310 Cedar St., New Haven, Conn., kindly send our trunk and go yourself to -- -- -- you know the rest.
Yale University School of Nursing
core   +1 more source

Stoneman, Xerxes: A Persian Life (Yale University Press, 2015)

open access: yesRoyal Studies Journal, 2017
Review of Richard Stoneman, Xerxes. A Persian Life (New Haven, CT: Yale University Press, 2015).
Mauro Serena
doaj   +1 more source

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