A clinical model for highly accurate prediction of blood glucose depression after continuous intravenous insulin therapy in hyperglycemic emergencies, a multicenter retrospective cohort study. [PDF]
This study developed a clinical model using a gradient boosting decision tree (GBDT) to predict blood glucose reduction (ΔGlu) after continuous intravenous insulin therapy in hyperglycemic emergencies. A multicenter retrospective cohort analysis identified key predictive factors, including initial blood glucose, bicarbonate concentration, insulin flow ...
Iwamoto Y +18 more
europepmc +2 more sources
Inflammatory Markers in Combination With Multiple Patterns of Extrarenal Extension Accurately Indicate Recurrence Risk in Patients With pT3aN0M0 Clear Cell Renal Cell Carcinoma. [PDF]
ABSTRACT Background and Aims A clear understanding of the risk of clear cell renal cell carcinoma (ccRCC) recurrence in individual patients is essential for appropriate administration of adjuvant therapy. Notably, non‐metastatic pT3a ccRCCs are heterogeneous, and affected patients will have a different prognosis depending on the pathological definition.
Uetani M +8 more
europepmc +2 more sources
Yamabe flow with prescribed scalar curvature [PDF]
In this work, we study the Yamabe flow corresponding to the prescribed scalar curvature problem on compact Riemannian manifolds with negative scalar curvature. The long time existence and convergence of the flow are proved under appropriate conditions on the prescribed scalar curvature function.
Inas Amacha, Rachid Regbaoui
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Anti-Lipogenic Effects of Iridoid-Rich Lonicera caerulea Berry Extracts in a Cortisol-Stimulated Adipocyte Model. [PDF]
ABSTRACT Berries of Lonicera caerulea (blue honeysuckle; haskap) have been used since ancient times in traditional medicine in China, Japan, and northern Russia. This study aimed to extract, characterize, and evaluate the biological activity of iridoid‐rich fractions from haskap berries using an in vitro adipocyte model.
Guo L +5 more
europepmc +2 more sources
Properties of Measurements of Patient-Reported Outcome Measures Physical Activity Assessment in Chronic Kidney Disease: A Systematic Review. [PDF]
ABSTRACT Background and Purpose The assessment of physical activity (PA) using Patient‐Reported Outcome Measures (PROMs) is routine due to its easy applicability and low cost. In the context of CKD, there are several studies that evaluate PA through PROM, but there is heterogeneity in the choice of tool.
Stella TC +4 more
europepmc +2 more sources
Long time existence of Yamabe flow on singular spaces with positive Yamabe constant [PDF]
We establish long-time existence of the normalized Yamabe flow with positive Yamabe constant on a class of manifolds that includes spaces with incomplete cone-edge singularities. We formulate our results axiomatically so that they extend to general stratified spaces as well, provided certain parabolic Schauder estimates hold.
Jørgen Olsen Lye, Boris Vertman
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Convergence of the CR Yamabe flow [PDF]
Accepted by Mathematische ...
Ho, Pak Tung, Sheng, Weimin, Wang, Kunbo
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Blood lactate as a marker of exercise adaptation and fatigue in male mice with chronic heart failure. [PDF]
Abstract Treadmill exercise tests assess aerobic capacity in chronic heart failure (CHF) mice, but subjective exhaustion criteria limit reproducibility. Elevated blood lactate (La) at exhaustion may provide an objective fatigue marker. This study evaluated La at exhaustion and the effects of exercise training (ExT) on resting La in CHF mice.
Wafi AM, Gao L, Zucker IH.
europepmc +2 more sources

