Results 31 to 40 of about 6,828,885 (247)

Integrating strategies of metabolomics, network pharmacology, and experiment validation to investigate the processing mechanism of Epimedium fried with suet oil to warm kidney and enhance yang

Frontiers in Pharmacology, 2023
Introduction: Epimedium, a traditional Chinese medicine (TCM) commonly used in ancient and modern China, is one of the traditional Chinese medicines clinically used to treat kidney yang deficiency syndrome (KYDS). There are differences in the efficacy of
E. Sun, E. Sun, Ran Huang, Ran Huang, Ke Ding, Ling Wang, Jian Hou, Xiaobin Tan, Xiaobin Tan, Yingjie Wei, Yingjie Wei, Liang Feng, Xiaobin Jia, Xiaobin Jia   +13 more
doaj   +1 more source

Global, regional and national burden of dietary iron deficiency from 1990 to 2021: a Global Burden of Disease study

Although iron deficiency is well documented, less is known about dietary involvement in symptomatic iron deficiency manifesting in medical conditions. In this study, we quantified the global burden of dietary iron deficiency, focusing on where inadequate
Adegboye, Oyelola A., Lee, Sooji, Addo, Isaac Yeboah, Abate, Semagn Mekonnen, Abate, Yohannes Habtegiorgis, Abie, Alemwork, Abukhadijah, Hana J., Adzigbli, Leticia Akua, Abouzid, Mohamed, Agyemang-Duah, Williams, Kim, Min Seo, Abualruz, Hasan, Ahmad, Aqeel, Abdullahi, Auwal, ElHafeez, Samar Abd, Abiodun, Olumide, Aburuz, Salahdein, Abebe, Mesfin, Ahmed, Syed Anees, Abdulkader, Rizwan Suliankatchi, Adnani, Qorinah Estiningtyas Sakilah, Son, Yejun, Fischer, Florian, Abedi, Armita, Adamu, Lawan Hassan, Abu-Zaid, Ahmed, Akinosoglou, Karolina, Agampodi, Suneth Buddhika, Abd-Elsalam, Sherief, Ahmad, Muayyad M., Abreu, Lucas Guimarães, Yon, Dong Keon, Aboagye, Richard Gyan, Shin, Jae Il, Ahmed, Ali, Akter, Ema, Abolhassani, Hassan, Hwang, Jiyoung, Abdoun, Meriem, Adane, Mesafint Molla, Ahmad, Shahzaib, Ahmad, Tauseef, Ahmed, Mehrunnisha Sharif, Ajami, Marjan, Adetunji, Charles Oluwaseun, Adekanmbi, Victor, Afzal, Saira, Ahmed, Haroon, Adeyeoluwa, Temitayo Esther, Ahmed, Ayman   +49 more
core   +3 more sources

Selective measurement of anti-tTG antibodies in coeliac disease and IgA deficiency : an alternative pathway [PDF]

, 2013
Objective To determine the ability of selective antibody testing to screen for coeliac disease in the presence of IgA deficiency and to define the sensitivity of a pathway using this method (Figure1).
Arasaradnam, Ramesh P., Nwokolo, Chuka U., Harrison, Elizabeth, Loft, Duncan, Liu, Kuo-Kang, Petchey, Michael   +5 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Proteomics analysis of IBS-D with spleen and kidney yang deficiency

Journal of Traditional Chinese Medical Sciences, 2017
Objective: To investigate the molecular mechanism underlying the development of diarrhea-predominant irritable bowel syndrome (IBS-D) with spleen and kidney yang deficiency (SKYD) using a proteomics approach.
Yijie Li, Xiaolan Su, Peng Wu, Jifeng Wang, Yu Guo, Jiajie Zhu, Qingguo Wang, Jiande Chen, Fuquan Yang, Wei Wei   +9 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Exploration of Constitutional Bias and Associated Factors in Patients with Recurrent and Metastatic Gastric Cancer, and the Therapeutic Effect of Prescription: A one-arm study

Integrative Cancer Therapies
Objective: This study was conducted to elucidate the distribution characteristics of predominant unbalanced constitutions and TCM syndrome elements in patients with recurrent and metastatic gastric cancer.
Luchang Cao, Xinmiao Wang, Xinyi Ma, Guanghui Zhu, Jie Li   +4 more
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

The relationship between traditional Chinese medicine constitution and indexes in chronic obstructive pulmonary disease patients: a systematic review and network meta-analysis

Frontiers in Medicine
ObjectiveTo investigate the characteristics of Chronic Obstructive Pulmonary Disease (COPD) patients with different Traditional Chinese Medicine (TCM) constitutions by analyzing the differences of indexes (smoking index, ratio of forced expiratory volume
Sheng Xie, Meiling Xie, Guanhong Li, Yu Zhang, Hui Wang, Yuqiong Zheng   +5 more
doaj   +1 more source