Results 181 to 190 of about 53,520 (304)

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

open access: yesAdvanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies   +14 more
wiley   +1 more source

Scalable Mie-Silk textile for dual-mode personal cooling indoors and outdoors. [PDF]

open access: yesSci Adv
Wang Y   +16 more
europepmc   +1 more source

Knitted Pneumatic Fabrics for Dynamic Pressure Modulation in Personalized Healthcare Wearables

open access: yesAdvanced Science, EarlyView.
A pneumatic pressure‐regulating knitted fabric (PPKF) is developed, in which knitted pneumatic circuit enables the seamless integration of ultralow radial expansion pneumatic fiber into dual‐channel textile structure. By strategically modulating channel spacing, delivering adjustable dynamic pressures and clinically relevant gradient compression ratios.
Xiaoyu Chen   +5 more
wiley   +1 more source

Dual‐Responsive Dynamic Covalent Bond‐Based Assembly of Lipid‐Nanozyme Systems via Multi‐Target Synergy and Efficient Target Enrichment for Ischemic Stroke Therapy

open access: yesAdvanced Science, EarlyView.
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo   +9 more
wiley   +1 more source

Decoding Naturalistic Episodic Memory with Artificial Intelligence and Brain‐Machine Interface

open access: yesAdvanced Science, EarlyView.
Episodic memory weaves together what, where, and when of experience into a personal narrative. Cutting‐edge AI models may decode this intricate process in real‐life settings, revealing how neural activity encodes naturalistic memories. By merging AI with brain–machine interfaces, researchers are edging closer to mapping and even engineering memory ...
Dong Song
wiley   +1 more source

Diabetic Socks: A Systematic Review of the Literature and Commercially Available Products. [PDF]

open access: yesDiabetes Metab Res Rev
Venkatraman PD   +9 more
europepmc   +1 more source

The ITGB2‐COPS3‐SOX2 Axis and SOX2 Liquid‐Liquid Phase Separation: Dual Mechanisms Governing Osteosarcoma Stemness

open access: yesAdvanced Science, EarlyView.
Osteosarcoma stemness is driven by the ITGB2‐COPS3‐SOX2 signaling axis. This study reveals that nuclear COPS3 stabilizes SOX2, which in turn undergoes liquid‐liquid phase separation to promote stemness. Based on this mechanism, a novel COPS3 inhibitor, Z‐5891, was developed, effectively suppressing tumor growth and stemness in vivo, offering a ...
Lei Guo   +7 more
wiley   +1 more source

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