Results 51 to 60 of about 239,587 (329)

Purkinje Cell Loss in Essential Tremor: Collective Data From 215 Brains Over a 21‐Year Period

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Essential tremor is a highly prevalent movement disorder. Pathological changes observed in essential tremor cerebella center around Purkinje cells and neighboring neuronal populations. Postmortem studies have variably, but not always, shown reduced Purkinje cell counts in essential tremor compared to controls.
Chloë A. Kerridge   +4 more
wiley   +1 more source

Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich   +10 more
wiley   +1 more source

Circular 02/07 : finance : further education colleges : accounting policies and return of audited financial statements [PDF]

open access: yes, 2002
"The purpose of this circular is to provide guidance to colleges and external auditors on the preparation of colleges’ annual financial statements. The Council has consulted the major providers of external audit services and sector representatives on ...

core  

Economic and Water Supply Effects of Ending Groundwater Overdraft in California's Central Valley

open access: yesSan Francisco Estuary and Watershed Science, 2016
doi: http://dx.doi.org/10.15447/sfews.2016v14iss1art7Surface water and groundwater management are often tightly linked, even when linkage is not intended or expected. This link is especially common in semi-arid regions, such as California.
Timothy Nelson   +5 more
doaj  

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam   +6 more
wiley   +1 more source

The divergent advancements of sap phenology in maple under warming conditions can shorten the sugar season

open access: yesTrees, Forests and People
Climate change raises concerns for the maple syrup industry, mainly regarding the expected changes in the timings of the sugar season and the resulting uncertainty of sap yield. This study investigates the temporal relationships between the environmental
Sara Yumi Sassamoto Kurokawa   +5 more
doaj   +1 more source

SELECTION IN SPORT - FOOTBAL [PDF]

open access: yesSport Mont, 2009
Qualitative system children and youth sports’ training in most of the countries contain well defined procedure of selection top-level sportsman. In developed countries basis of prestige include well organized football schools in which selected groups of ...
Velimir Vukajlović
doaj  

Profitability of forestry in jointly-owned forests of Northeastern Finland and Lapland.

open access: yesSilva Fennica, 1992
The profitability of jointly owned forest holdings in the two northernmost forest board districts of Finland was studied by means of ratio analysis. A time series of profit and loss statements and balance sheets from 33 holdings covering the fiscal years
Penttinen, Markku, Kinnunen, Matti
doaj   +1 more source

Year-End Reflections [PDF]

open access: yesChemical & Engineering News Archive, 1998
This has been a special year for C&EN as it celebrated its 75th anniversary. We are fond of referring to it as our Halley's comet year—that is, once in a lifetime. We tried to make the most of it, and our readers helped us do just that. So as we publish this, the last issue of C&EN in 1998, we thought we'd take a few moments to reflect on what we tried
openaire   +1 more source

Amyotrophic Lateral Sclerosis Prevalence Projection in 2040: A Less Rare Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To project ALS prevalence across multiple countries through 2040, accounting for both population aging and increased survival. Methods Data from the Piemonte and Valle d'Aosta ALS register (PARALS) was used to estimate the trends in incidence and prevalence from 2005 to 2019. Survival trends over this period were also assessed.
Rosario Vasta   +18 more
wiley   +1 more source

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