Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu +16 more
wiley +1 more source
Autosomal Recessive Spastic Ataxia of Charlevoix‐Saguenay in Two Half‐Siblings
ABSTRACT Autosomal recessive spastic ataxia of Charlevoix‐Saguenay (ARSACS) is caused by biallelic pathogenic variants in the SACS gene. We report the clinical, radiologic and neurophysiologic features of a pair of half‐siblings who presented with progressive cerebellar ataxia, peripheral neuropathy and upper motor neuron signs.
Dennis Yeow +6 more
wiley +1 more source
A Case of Caudal Regression Syndrome From Pakistan
Background: Caudal regression syndrome is a group of defects with incomplete development of the terminal vertebral column, with an incidence of 1 in 60,000 live births.
Sheharyar Zameer +5 more
doaj +1 more source
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan +22 more
wiley +1 more source
20th Anniversary of the Polish Section of the Audio Engineering Society
In June 2011, Polish Section of the Audio Engineering Society will celebrate its 20th anniversary. On this occasion, the society officers, ending their second, two-year term, present a short summary of the Section’s activity during the past four years.
Zbigniew KULKA +3 more
doaj
Canada contributed $26,700,000 to humanitarian and emergency relief efforts in the fiscal year ending March 31, 1982. Funds amounting to $7,775,000 were provided as annual contributions to United Nations humanitarian organizations and the ...
Refuge Editor
doaj +1 more source
Domain Specific Placebo Response in the Modified Friedreich's Ataxia Rating Scale
ABSTRACT The placebo response in clinical trials in ataxias complicates outcome interpretation and potentially obscures genuine treatment effects. We analyzed placebo group data from past trials in Friedreich Ataxia and observed notable responses in appendicular items, in contrast to minimal changes in axial function, as measured by respective ...
Christian Rummey +2 more
wiley +1 more source
A Survey of the Complaints Entering the Medical Council Organization of Tehran in Three Time Periods: The Years Ending on 20 March 1992, 20 March 1997 and 20 March 2002 [PDF]
One of the most important occupational tensions a physician encounters in his/her practice is the complaints lodged against him/her by the patients.
Ali Jafarian +5 more
doaj +1 more source
Multi‐Omics Integration for Advancing Glioma Precision Medicine
ABSTRACT Gliomas are among the most malignant and aggressive tumors of the central nervous system, characterized by the absence of early diagnostic markers, poor prognosis, and a lack of effective treatments. Advances in high‐throughput technologies have facilitated a refined molecular classification of gliomas, incorporating genetic features. However,
Maria Guarnaccia +4 more
wiley +1 more source
Studies on the toxic elements and organic degradation products in aquatic bodies and sediments around Kennedy Space Center (KSC) Haulover Canal and Mosquito Lagoon [PDF]
The work during the first year ending September, 1975, is reported. Indian River, Haulover Canal, Mosquito Lagoon, and other aquatic areas of discharge around Kennedy Space Center (KSC) were studied.
Emeh, C. O., Ghuman, G. S., Menon, M. P.
core +1 more source

