Results 61 to 70 of about 241,695 (330)
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
A Case of Caudal Regression Syndrome From Pakistan
European Medical Journal Reproductive HealthBackground: Caudal regression syndrome is a group of defects with incomplete development of the terminal vertebral column, with an incidence of 1 in 60,000 live births.
Sheharyar Zameer +5 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
20th Anniversary of the Polish Section of the Audio Engineering Society
Archives of Acoustics, 2013 In June 2011, Polish Section of the Audio Engineering Society will celebrate its 20th anniversary. On this occasion, the society officers, ending their second, two-year term, present a short summary of the Section’s activity during the past four years.
Zbigniew KULKA +3 more
doaj
Refuge, 1982 Canada contributed $26,700,000 to humanitarian and emergency relief efforts in the fiscal year ending March 31, 1982. Funds amounting to $7,775,000 were provided as annual contributions to United Nations humanitarian organizations and the ...
Refuge Editor
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
A Survey of the Complaints Entering the Medical Council Organization of Tehran in Three Time Periods: The Years Ending on 20 March 1992, 20 March 1997 and 20 March 2002 [PDF]
Journal of Medical Ethics and History of Medicine, 2009 One of the most important occupational tensions a physician encounters in his/her practice is the complaints lodged against him/her by the patients.
Ali Jafarian +5 more
doaj +1 more source
Studies on the toxic elements and organic degradation products in aquatic bodies and sediments around Kennedy Space Center (KSC) Haulover Canal and Mosquito Lagoon [PDF]
The work during the first year ending September, 1975, is reported. Indian River, Haulover Canal, Mosquito Lagoon, and other aquatic areas of discharge around Kennedy Space Center (KSC) were studied.
Emeh, C. O., Ghuman, G. S., Menon, M. P.
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source