Results 181 to 190 of about 68,199 (344)
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich +10 more
wiley +1 more source
An inter-city input-output database distinguishing firm ownership in the Greater China area during 2002-2017. [PDF]
Wang Y +16 more
europepmc +1 more source
Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam +6 more
wiley +1 more source
Spatial distribution characteristics and tourism response of intangible cultural heritage in coastal areas of China. [PDF]
Xie L, Feng T, Jiang L, Tian J.
europepmc +1 more source
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini +13 more
wiley +1 more source
Increasing excess mortality among non-married elderly people in developed countries
This article analyses changes in marital status differences in mortality from approximately 1970 to 1995 among men and women aged 65-74 in ten developed countries (Belgium, Canada, Denmark, England and Wales, Finland, France, Japan, Netherlands, Norway ...
doaj
Who is saving our streamflow data? Exploring volunteer profiles and their engagement in the SIREN data rescue project. [PDF]
Mazzoglio P +7 more
europepmc +1 more source

