Results 81 to 90 of about 446,034 (255)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Environmentally sustainable white, green and blue analytical method for simultaneous determination of ciprofloxacin and hydrocortisone using MVAS approach

open access: yesDiscover Chemistry
This study outlines the development of an environmentally sustainable green, white and blue analytical method for the simultaneous determination of Ciprofloxacin and Hydrocortisone in eardrop using the absorption ratio i.e. Q-analysis method, adhering to
Kondreddy Vinod Kumar   +2 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Cardinal of 1913; Cardinal (Fayetteville, Ark.)

open access: yes, 1913
16The University of Arkansas, Fayetteville yearbook was first published in 1897 as the Cardinal. The Cardinal was published through 1915, and in 1916 the name of the yearbook was changed to the Razorback.This material may depict ethnic, racial, and ...

core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Flood prevention on the lower reaches of the Rellow River

open access: yes, 1990
Proceedings of a congerence in Zhenzhou, China, 1990: Gong Shiyan, Wu Zhiyao: Introduction. Bao Zicheng, Zhang Mingde, Wang Rudiu: Strenghtening of dykes by Warping.
Shiyang, Gong (author)   +1 more
core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Cardinal Life Game cards

open access: yes, 2009
These game cards are associated with the "Cardinal Life game" also available in Cardinal Scholar at http://cardinalscholar.bsu.edu/566/ The GIS Research and Map Collection created this board game featuring an aerial map of the Ball State University ...

core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

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