Results 11 to 20 of about 602,894 (213)
Yellow fever outbreak, Imatong, southern Sudan. [PDF]
In May 2003, the World Health Organization received reports about a possible outbreak of a hemorrhagic disease of unknown cause in the Imatong Mountains of southern Sudan.
Sang, Rosemary C +24 more
core +1 more source
Phylogeny of Yellow Fever Virus, Uganda, 2016
In April 2016, a yellow fever outbreak was detected in Uganda. Removal of contaminating ribosomal RNA in a clinical sample improved the sensitivity of next-generation sequencing. Molecular analyses determined the Uganda yellow fever outbreak was distinct
Holly R. Hughes +5 more
doaj +1 more source
The thermal stability of yellow fever vaccines
The assessment of yellow fever vaccine thermostability both in lyophilized form and after reconstitution were analyzed. Two commercial yellow fever vaccines were assayed for their thermal stability. Vaccines were exposed to test temperatures in the range
Ricardo Ishak, Colin R. Howard
doaj +1 more source
Background: Prevention of Yellow Fever (YF) in travellers to Yellow Fever endemic zone can be done with YF 17D vaccine which is a live attenuated vaccine and can be given only up to one hour after reconstitution.
Dhananjay Kumar +5 more
doaj +1 more source
Background: Yellow fever is an arboviral haemorrhagic disease transmitted by mosquitoes in the tropical regions of Africa and South America. WHO estimates that there are 200 000 severe cases and 30 000 deaths worldwide annually. In Brazil, the wild cycle
André Luís Acosta, PhD +4 more
doaj +1 more source
Anamnestic immune response to dengue and decreased severity of yellow fever
A protective immunity against yellow fever, from cross-reactive dengue antibodies, has been hypothesized as an explanation for the absence of yellow fever in Southern Asia where dengue immunity is almost universal.
Ricardo O Izurieta +7 more
doaj +1 more source
Descriptive Characterization of Suspected Yellow Fever Cases in Kano state, Nigeria, 2015-2018
Introduction: Yellow fever remains a serious public health problem globally with an estimated 200, 000 cases annually despite the availability of an effective vaccine for more than 70 years. Nigeria had an outbreak of Yellow fever in 2017 after more than
Usman Yahya Umar +4 more
doaj +1 more source
Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron
Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej +20 more
wiley +2 more sources
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song +5 more
wiley +1 more source
Deltacoronavirus Modulates circRNA cGLIS3 Metabolism to Evade Host Antiviral Response
This study reveals that both deltacoronavirus nucleocapsid protein and host RNA binding protein IGF2BP2 promote circular RNA GLIS3 (cGLIS3) biogenesis by binding to GLIS3 pre‐mRNA. The m6A modification‐mediated cGLIS3‐IGF2BP2 interaction weakens RNase L‐mediated degradation of cGLIS3 while facilitates a ubiquitin‐dependent degradation of IGF2BP2, thus ...
Liuyang Du +10 more
wiley +1 more source

