Results 71 to 80 of about 323,328 (291)

OGFRL1 Deficiency Causes Chronic Recurrent Multifocal Osteomyelitis Via Pathologic Osteoclastogenesis, With Therapeutic Response to Tumor Necrosis Factor Inhibitor

Arthritis &Rheumatology, EarlyView.
Objective To verify the pathogenesis of the opioid growth factor receptor like‐1 (OGFRL1) loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a patient with chronic recurrent multifocal osteomyelitis (CRMO) and to investigate the underlying mechanism.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

Controvérsias sobre a ampliação das áreas com vacinação de rotina contra a febre amarela no Brasil

Cadernos de Saúde Pública
Resumo: Febre amarela é uma doença viral potencialmente grave, transmitida por mosquitos Haemagogus, Aedes e Sabethes. A vacinação é a medida mais importante para a sua prevenção e controle.
Tatiana Guimarães de Noronha, Luiz Antonio Bastos Camacho   +1 more
doaj   +1 more source

The yellow fever epidemic of 1800 and its impact on La Carlota, capital of the New Settlements of Andalusia [PDF]

, 2018
Las sociedades de finales del Antiguo Régimen se vieron amenazadas por diferentes enfermedades, siendo la fiebre amarilla una de las más temidas por su letalidad.
Hamer-Flores, Adolfo
core   +3 more sources

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still's Disease‐like Autoinflammatory Syndrome

Arthritis &Rheumatology, Accepted Article.
Objectives Still's Disease represents a prototypical polygenic systemic autoinflammatory diseases (SAIDs), characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still's disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source

Yellow Fever outbreaks in unvaccinated populations, Brazil, 2008-2009.

PLoS Neglected Tropical Diseases, 2014
Due to the risk of severe vaccine-associated adverse events, yellow fever vaccination in Brazil is only recommended in areas considered at risk for disease.
Alessandro Pecego Martins Romano, Zouraide Guerra Antunes Costa, Daniel Garkauskas Ramos, Maria Auxiliadora Andrade, Valéria de Sá Jayme, Marco Antônio Barreto de Almeida, Kátia Campomar Vettorello, Melissa Mascheretti, Brendan Flannery   +8 more
doaj   +1 more source

The obscurance of the greatest sylvatic yellow fever epidemic and the cooperation of the Pan American Health Organization during the COVID-19 pandemic

Revista da Sociedade Brasileira de Medicina Tropical, 2020
INTRODUCTION: Since 2016, Brazil has been in the midst of its largest sylvatic yellow fever epidemic ever, found predominantly outside the Amazon region.
Carlos Frederico Campelo de Albuquerque e Melo, Pedro Fernando da Costa Vasconcelos, Luiz Carlos Júnior Alcantara, Wildo Navegantes de Araujo   +3 more
doaj   +1 more source

Critical aspects of yellow fever control in Brazil [PDF]

, 2010
São apresentados aspectos epidemiológicos e do controle da febre amarela no Brasil, considerando os ciclos de transmissão silvestre e urbano. Sem registros de transmissão no Brasil desde 1942, houve casos de febre amarela urbana em 2008 no Paraguai ...
Tauil, Pedro Luiz
core   +2 more sources

ProTides for Antiviral Activity Beyond Liver Cells

Chemistry – A European Journal, EarlyView.
A strategy for obtaining prodrugs of antiviral nucleotides with broad tissue activity is presented that relies on cycloalkyl or cycloalkylalkyl esters, improving uptake and esterase cleavage, and producing nanomolar inhibitors in kidney, colon, and lung cells.
Felix Goebel, Adrian Humboldt, Heeyoung Kim, Carl J. M. Schölzel, Ralf Bartenschlager, Clemens Richert   +5 more
wiley   +1 more source

Magic Portraits Drawn by the Sun: New Orleans and the sense(s) of death in Josh Russell’s Yellow Jack [PDF]

, 2011
In ways comparable to the horrors of Hurricane Katrina and its aftermath in 2005, the series of yellow fever epidemics that devastated New Orleans through the nineteenth century were also the result, in part, of the city?s geographical position, its ...
Robinson, O
core  

When Heredity Met the Bacterium: Quarantines in New York and Danzig, 1898-1921 [PDF]

, 2001
[Excerpt] Recent careful examinations of American quarantines placed on incoming migrants have found that health officials were potent carries of bigotries rooted in the larger society; but usually historians have not paid sufficient attention to the ...
Korman, Gerd
core   +2 more sources