Results 71 to 80 of about 125,648 (262)

Host-Specific NS5 Ubiquitination Determines Yellow Fever Virus Tropism [PDF]

, 2019
The recent yellow fever virus (YFV) epidemic in Brazil in 2017 and Zika virus (ZIKV) epidemic in 2015 serve to remind us of the importance of flaviviruses as emerging human pathogens. With the current global flavivirus threat, there is an urgent need for
Albrecht, Randy A, Co, Pierre Hendrick, García-Sastre, Adolfo, Laurent-Rolle, Maudry, Miorin, Lisa, Morrison, Juliet, Pisanelli, Giuseppe   +6 more
core   +2 more sources

ProTides for Antiviral Activity Beyond Liver Cells

Chemistry – A European Journal, EarlyView.
A strategy for obtaining prodrugs of antiviral nucleotides with broad tissue activity is presented that relies on cycloalkyl or cycloalkylalkyl esters, improving uptake and esterase cleavage, and producing nanomolar inhibitors in kidney, colon, and lung cells.
Felix Goebel, Adrian Humboldt, Heeyoung Kim, Carl J. M. Schölzel, Ralf Bartenschlager, Clemens Richert   +5 more
wiley   +1 more source

Oral Susceptibility to Yellow Fever Virus of Aedes aegypti from Brazil

Memorias do Instituto Oswaldo Cruz, 2002
The oral susceptibility to yellow fever virus was evaluated in 23 Aedes aegypti samples from Brazil. Six Ae. aegypti samples from Africa, America and Asia were also tested for comparison.
Ricardo Lourenço-de-Oliveira, Marie Vazeille, Ana Maria Bispo de Filippis, Anna-Bella Failloux   +3 more
doaj   +1 more source

Circulation of antibodies against yellow fever virus in a simian population in the area of Porto Primavera Hydroelectric Plant, São Paulo, Brazil Circulação de anticorpos contra o vírus amarílico em população simiana da região da usina hidrelétrica de Porto Primavera, São Paulo, Brasil

Revista do Instituto de Medicina Tropical de São Paulo, 2010
Yellow fever (YF) is an acute viral infectious disease transmitted by mosquitoes which occurs in two distinct epidemiological cycles: sylvatic and urban.
Maura Antonia Lima, Nicolina Silvana Romano-Lieber, Ana Maria Ribeiro de Castro Duarte   +2 more
doaj   +1 more source

Examining Zika Virus: Transmission, Diagnosis, Treatment, and Prevention [PDF]

, 2020
The Zika virus is a mosquito-borne virus that was first isolated in Uganda in 1947 and has since caused outbreaks in many parts of the world. It has multiple routes of transmission and may cause acute illness and death if not treated.
Taybeh, Noura
core   +1 more source

Zika virus infection reprograms global transcription of host cells to allow sustained infection. [PDF]

, 2017
Zika virus (ZIKV) is an emerging virus causally linked to neurological disorders, including congenital microcephaly and Guillain-Barré syndrome. There are currently no targeted therapies for ZIKV infection.
Bansal, Vikas, Dang, Jason, Lichinchi, Gianluigi, Qin, Yue, Rana, Tariq M, Tiwari, Shashi Kant   +5 more
core   +2 more sources

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Yellow Jack: a modern threat to Asia-Pacific countries?

npj Viruses
In 1923, H.R. Carter published a seminal treatise on the possibility of yellow fever virus spreading to the Asia Pacific region, where large numbers of susceptible people were at risk of infection.
Duane J. Gubler, Kathryn A. Hanley, Thomas P. Monath, David M. Morens, Mauricio Lacerda Nogueira, Nikos Vasilakis, Scott C. Weaver, Yellow Fever Advisory Group   +7 more
doaj   +1 more source

Neuropathology of yellow fever autopsy cases

Tropical Diseases, Travel Medicine and Vaccines, 2023
Background Yellow fever is a viral hemorrhagic fever caused by yellow fever virus, a mosquito-borne flavivirus. Despite an effective vaccine, major outbreaks continue to occur around the world.
Fernando Pereira Frassetto, Sergio Rosemberg   +1 more
doaj   +1 more source

Emerging Challenges and Opportunities in Infectious Disease Epidemiology. [PDF]

, 2019
Much of the intellectual tradition of modern epidemiology stems from efforts to understand and combat chronic diseases persisting through the 20th century epidemiologic transition of countries such as the United States and United Kingdom.
Lewnard, Joseph A, Reingold, Arthur L
core