Results 111 to 120 of about 1,980,439 (259)

Protein Corona Engineering of Lipid Nanoparticles Enables Efficient Functional Gene Silencing in the Liver

Small, EarlyView.
By shaping the protein corona, lipid composition directs LNP tropism and enables the preferential delivery of a TIMP1‐targeting siRNA to liver macrophages. In a murine model of primary biliary cholangitis, this strategy promoted macrophage reprogramming and attenuated liver fibrosis.
Naths G. Sukubo, Serena Renzi, Martina B. Violatto, Leila Altigieri, Anna L. Capriotti, Andrea Cerrato, Aldo Laganà, Luca Digiacomo, Erica Quagliarini, Antonio Minopoli, Massimiliano Papi, Daniela Pozzi, Carlo A. Scirè, Pietro Invernizzi, Paolo Bigini, Giulio Caracciolo   +15 more
wiley   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source

Water and poverty in China’s Yellow river basin

, 2015
Rapid economic growth in the Yellow River Basin (YRB) of China has put intense demands on Yellow River waters. By far the largest user of water resources is the agricultural sector, accounting for 80 percent of total withdrawals—with industrial, urban ...
http://orcid.org/0000-0002-0112-502X Ahmed, A., Ahmed, Akhter U.; Wang, Jinxia; Bhaskar, Anjor; Quabili, Wahid   +1 more
core  

A dual‐responsive fluorescent probe for imaging viscosity and polarity in nonalcoholic fatty liver disease

Smart Molecules, EarlyView.
We developed a BODIPY‐based fluorescent probe with dual responsiveness to viscosity and polarity, enabling sensitive and precise imaging of non‐alcoholic fatty liver disease. Abstract Viscosity and polarity are critical physiological parameters implicated in the onset and progression of nonalcoholic fatty liver disease (NAFLD).
Di Zhao, Zhizhong Wang, Ke Xu, Yuntai Liu, Di Wu, Ting Jiang, Haonan Gao, Chengmei Xiao, Debin Zheng, Kai Wang, Wenhao Zhai   +10 more
wiley   +1 more source

Distribution of carbon, nitrogen and phosphorus in coastal wetland soil related land use in the Modern Yellow River Delta

, 2016
The delivery and distribution of nutrients in coastal wetland ecosystems is much related to the land use. The spatial variations of TOC, TN, NH4+-N, NO3--N and TP and associated soil salinity with depth in 9 kinds land uses in coastal zone of the modern ...
Wang, Guangmei, Yu, JB (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Processes & Ecol Remedia, Yantai 264003, Peoples R China. Email:junbao.yu@gmail.com, Yu, Junbao, Xing, Qinghui, Chu, Xiaojing, Guan, Bo, Zhou, Di, Yu, JB, Wang, Q (reprint author), Ludong Univ, Coll Resource & Environm Engn, Yantai 264025, Peoples R China., Wang, Qing, Zhan, Chao, Li, Yunzhao, schingwang@126.com, Han, Guangxuan, Fu, Yuqin   +14 more
core   +1 more source

Influence of natural fibers on physical, mechanical, and fire‐resistant properties of microconcrete

Structural Concrete, EarlyView.
Abstract This study examined the influence of natural fibers on the physical, mechanical, and fire‐resistant properties of microconcrete, in comparison with conventional polypropylene fibers used in cement composites. The fibers were characterized by FTIR and TGA/DSC to assess their composition and thermal stability, and FTIR was also performed after ...
Ivanka Netinger Grubeša, Sandra Juradin, Silvija Mrakovčić, Lidija Radovanović, Milica Vasić, Huseyin Bilgin   +5 more
wiley   +1 more source

Water productivity assessment for China's Yellow river basin

, 2017
The second longest river in China after the Yangtze, the Yellow River and its basin (YRB) is the breadbasket of China and the cradle of Chinese civilization. With only 2 percent of national water resources, the basin generated 14 percent of Chinese grain
Cai, Ximing; Yang, Yi-Chen E.; Ringler, Claudia; You, Liangzhi, http://orcid.org/0000-0002-8266-0488 Ringler, Claudia; http://orcid.org/0000-0001-7930-8814 You, Liangzhi   +1 more
core  

Ontogeny of foraging behaviour in an opportunistic gull inhabiting urban marine ecosystems

Wildlife Biology, EarlyView.
Urbanization affects ecosystems by reducing biodiversity and displacing species from native habitats. While some suffer, others, like urban wildlife, adapt through innovative feeding and behaviours that improve their fitness in human‐altered settings. Despite research on wildlife in urban areas, the development of foraging behaviour in urban species is
Joan Navarro, Víctor Martín-Vélez, Joan Giménez, José Antonio Garcia, Pablo Cermeño, Jordi Figuerola, Raül Aymí, Tomás Montalvo   +7 more
wiley   +1 more source

Cumulative Duration and Habitat Selection Across the Annual‐Cycle Stages: Links to Human Modification in Two Declining Shorebirds

Integrative Zoology, EarlyView.
First multi‐season analysis linking cumulative duration and habitat selection to human modification in two declining shorebirds. A total of 160 cumulative duration was identified at four periods for two species. Longer cumulative duration correlate with higher human modification in coastal wetlands during northward migration and winter.
Houlang Duan, Wenhan Wang, Qing Xiao, Bingrun Zhu, Shaoxia Xia, Zhengwang Zhang, Xiubo Yu   +6 more
wiley   +1 more source

From politics to economics: The investigation of the determinants of local administrative hierarchy in the Tang–Song transition

Asia‐Pacific Economic History Review, Volume 65, Issue 1, Page 39-78, March 2025.
Abstract This study collects original data to examine the determinants of classification criteria of county hierarchy and its rank variations during the Tang–Song period. The results reveal that the county hierarchy was affected by both economic and political situations, with more emphasis on politics in Tang and economics in Song.
Nan Li, Heqi Cai
wiley   +1 more source