Results 41 to 50 of about 122,090 (305)

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Modeling deltaic lobe‐building cycles and channel avulsions for the Yellow River delta, China [PDF]

, 2019
River deltas grow by repeating cycles of lobe development punctuated by channel avulsions, so that over time, lobes amalgamate to produce a composite landform.
Carlson, Brandee N., Chadwick, Austin J., Lamb, Michael P., Ma, Hongbo, Moodie, Andrew J., Nittrouer, Jeffrey A., Parker, Gary   +6 more
core  

Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction

Advanced Science, EarlyView.
During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao, Shenghui Huo, Yue Xing, Shuxin Zhang, Guilin Li, Yihui Liu, Chongyang Jin, Fuguang Li, Xiaoyang Ge   +8 more
wiley   +1 more source

Legumain Restrains Granuloma Formation by Inhibiting mTORC1/STAT1‐Mediated M1 Macrophage Polarization in Sarcoidosis

Advanced Science, EarlyView.
Legumain (LGMN) is upregulated in macrophages during sarcoid‑like granuloma formation. Macrophage‑derived LGMN binds to integrin αvβ3 and suppresses mTORC1/STAT1 signaling to restrain M1 macrophage polarization. Intratracheal delivery of lipid nanoparticles carrying Lgmn plasmid DNA (pDNA) elevates LGMN expression and effectively attenuates pulmonary ...
Mengyuan Liu, Yueyin Han, Bingbing Xie, Lili Zhu, Wenxiu Xu, Yinzhen Han, Yue Liao, Shuwei Gao, Dingyuan Jiang, Jing Geng, Zhen Li, Yinan Hu, Huaping Dai   +12 more
wiley   +1 more source

Composition, seasonal variation, and salinization characteristics of soil salinity in the Chenier Island of the Yellow River Delta

Global Ecology and Conservation, 2020
Coastal wetlands, which are fragile and intricate ecosystems with continuously changing salinity and moisture, are especially sensitive to climate changes and anthropogenic activities.
Zhanyong Fu, Ping Wang, Jingkuan Sun, Zhaohua Lu, Hongjun Yang, Jingtao Liu, Jiangbao Xia, Tian Li   +7 more
doaj   +1 more source

Temporal Interference Stimulation Enhances Neural Regeneration

Advanced Science, EarlyView.
Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressotti, Maria Garcia Garrido, Patrycja Dzialecka, Rachel Man Hoi Law, Roberto Portillo‐Lara, Bethany Geary, Elena Faillace, Shirine Merlo‐Nikpay Aslie, Marcelina Wojewska, Maria Otero‐Jimenez, Martina Genta, Luqiao Tan, Karen Duff, Javier Alegre‐Abarrategui, Rylie Green, Nir Grossmann   +15 more
wiley   +1 more source

Origin, evolution and biogeographic dynamics of the European rabbit (Oryctolagus cuniculus) in Southwestern Europe

The Anatomical Record, EarlyView.
Abstract The Pleistocene is a key period for understanding the evolutionary history and palaeobiogeography of the European rabbit (Oryctolagus cuniculus). The species was first documented in southeastern Iberia at the beginning of the Middle Pleistocene and appears to have rapidly spread throughout Southwestern Europe, where it was found in numerous ...
Maxime Pelletier
wiley   +1 more source

Pseudomonas aeruginosa L10: A Hydrocarbon-Degrading, Biosurfactant-Producing, and Plant-Growth-Promoting Endophytic Bacterium Isolated From a Reed (Phragmites australis)

Frontiers in Microbiology, 2018
Bacterial endophytes with the capacity to degrade petroleum hydrocarbons and promote plant growth may facilitate phytoremediation for the removal of petroleum hydrocarbons from contaminated soils.
Tao Wu, Tao Wu, Jie Xu, Wenjun Xie, Wenjun Xie, Zhigang Yao, Zhigang Yao, Hongjun Yang, Chunlong Sun, Chunlong Sun, Xiaobin Li   +10 more
doaj   +1 more source

Plant Rhizospheres Harbour Specific Fungal Groups and Form a Stable Co-Occurrence Pattern in the Saline-Alkali Soil

Agronomy, 2023
Soil salinisation has been considered a substantial ecosystem issue with negative effects on sustainable agricultural practices. Practices of vegetation restoration are widely conducted for coping with saline soil degradation, especially in saline-alkali
Zhen Liu, Jing Li, Ruixing Hou, Yitao Zhang, Huarui Gong, Yanfei Sun, Zhu Ouyang, Zhigang Sun   +7 more
doaj   +1 more source

A Geomorphometric Approach to Estimate the Deterioration of Earthen Archaeological Sites by Rainfall and Diffusion Processes: The Huaca Chornancap (Eighth–14th Century ad), Lambayeque, Peru

Archaeological Prospection, EarlyView.
ABSTRACT Rain‐induced erosion processes can severely damage Earthen archaeological sites. Huaca Chornancap (HCH; eighth–14th century ad) is a platform located in the Lambayeque region (Peru) exposed to seasonal rain due to El Niño Southern Oscillation (ENSO).
Luigi Magnini, Maria Ilaria Pannaccione Apa, Robert Gutiérrez Cachay, Marco Fernández Manayalle, Carlos Eduardo Wester La Torre, Guido Ventura   +5 more
wiley   +1 more source