Results 71 to 80 of about 1,866,769 (265)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Comprehensive analysis of dehydrin genes reveals ZmDHN3 contributes to drought resistance in maize (Zea Mays L.)

open access: yesBMC Plant Biology
Background Dehydrin (DHN) proteins, belong to subfamily members of late embryogenesis abundant (LEA) proteins, are widely recognized as key determinants in plant abiotic stress tolerance.
Yongfeng Xie   +4 more
doaj   +1 more source

Methods of analysis of a reinforced concrete section under bending with axial force in the post-yield range

open access: yesBudownictwo i Architektura, 2014
Predicting the behaviour of plastic hinges subjected to large inelastic deformations caused by extreme loads such as earthquakes plays an important role in assessing maximum stable deformation capacities of framed concrete structures. This paper presents
Jacek Korentz
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Artificially induced drought stress affects seasonal foliar litterfall, nutrient contents, and nutrient masses in mature European beech (Fagus sylvatica [L.]) and Norway spruce (Picea abies [L.] Karst.)

open access: yesTrees, Forests and People
We examined the effects of drought-induced stress on foliar litter production, nutrient contents, and nutrient masses in mature European beech (Fagus sylvatica [L.]) and Norway spruce (Picea abies [L.] Karst.) over a two-year period (October 2015 ...
Matthias Ulbricht   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

OPTIMIZA TION OF UNEVEN - AGED FIR STANDS AND ITS IMPORTANCE IN MANAGEMENT

open access: yesForestist, 1992
Here, a method is offered to obtain optimum structures for fir selectiorı forests. The natural relationships that eurrently run in unevenaged tir stands of southern Black Sea Region were based on in the ealculations of the optimum structures whieh ...
Ömer Saraçoğlu
doaj   +2 more sources

Mathematical Modeling of the Mojave Solar Plants

open access: yesEnergies, 2019
Competitiveness of solar energy is one of current main research topics. Overall efficiency of solar plants can be improved by using advanced control strategies.
Antonio J. Gallego   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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