Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
MOVING FROM UNIFORM TO VARIABLE FERTILIZER RATES ON IOWA CORN: EFFECTS ON RATES AND RETURNS
This study develops a model based on the yield potential of various soil types in 12 Iowa counties to estimate the potential value of switching from uniform to variable fertilizer rates.
Babcock, Bruce A., Pautsch, Gregory R.
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Further evidence on the impact of economic news on interest rates [PDF]
US interest rates'overnight reaction to macroeconomic announcements is of tremendous importance trading fixed income securities. Most of the empirical studies achieved so far either assumed that the interest rates' reaction to announcements is linear or ...
Dominique Guegan, Florian Ielpo
core
Effects of soil layer replacement combined with organic fertilizer application on soil quality and maize yield in heavy metal-contaminated farmland. [PDF]
iScienceWang H, Tu H, Wang P, Li X, Wu P.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Black thread disease, control measures and yield stimulation in Hevea brasiliensis in Liberia
, 1972 Described are investigations, carried out in 1963 to 1971 in Hevea brasiliensis at the Firestone Plantation at Harbel in Liberia. Studied was the tapping panel disease, black thread, caused by the fungus Phytophthora palmivora.
Schreurs, J.
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Evaluation of salt stress indices and morpho-physiological attributes to identify high-yielding, salt-tolerant guar (Cyamopsis tetragonoloba L.) genotypes. [PDF]
Sci RepNajm MR +5 more
europepmc +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source