Results 101 to 110 of about 1,488,092 (350)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
What Drives the Nominal Yield Curve in Brazil?
, 2021 Marcelo Fernandes +2 more
openalex +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
An extended macro-finance model with financial factors. [PDF]
This paper extends the benchmark Macro-Finance model by introducing, next to the standard macroeconomic factors, additional liquidity-related and return forecasting factors.
Dewachter, Hans, Iania, Leonardo
core +3 more sources
AIP Advances, 2018 Finite element analysis (FEA) was performed to study the wear fatigue resistance of gradient structures (GSs) with different types of yield strength distributions under rolling-sliding contact. We found that the GS layer can reduce the plastic strain and
Jian Wang, Qimin Li
doaj +1 more source
Using the Entire Yield Curve in Forecasting Output and Inflation
Econometrics, 2018 In forecasting a variable (forecast target) using many predictors, a factor model with principal components (PC) is often used. When the predictors are the yield curve (a set of many yields), the Nelson–Siegel (NS) factor model is used in place of ...
Eric Hillebrand +3 more
doaj +1 more source
A yield curve perspective on uncovered interest parity [PDF]
, 2006 This article uses a dynamic multi-factor model of the yield curve with a rational-expectations, general-equilibrium-economy foundation to investigate the uncovered interest parity hypothesis(UIPH).
Krippner, Leo
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Yield Curve Dynamics: Regional Common Factor Model [PDF]
In this paper, we focus on thorough yield curve modelling. We build on extended classical Nelson-Siegel model, which we further develop to accommodate unobserved regional common factors.
Boril Šopov, Jakub Seidler
core +1 more source